000			03086nam a22003975i 4500
001			394618
003			ES-MaUEC
005			20230102123143.0
007			cr nn 008mamaa
008			221212s2022 sz | s |||| 0|eng d
020			_a9783031106910
024	7		_a10.1007/978-3-031-10691-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
100	1		_aKhojasteh, S. Cyrus _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut
245	1	0	_aDiscovery DMPK Quick Guide _bGuide to Data Interpretation and integration _cby S Cyrus Khojasteh, Harvey Wong, Donglu Zhang, Cornelis ECA Hop
250			_a1st edition 2022
264		1	_aCham _bSpringer International Publishing _c2022
300			_a1 recurso en línea (XXI, 228 páginas) _b129 ilustraciones, 59 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
505	0		_aGoals for DMPK during drug optimizations -- Drug Properties -- DMPK in lead optimization -- Candidate tranlational characterization -- Q&A of DMPK issues and tools for drug discovery -- ADME assays -- Regulatory documents for IND to Support FIH -- Appendix: Chemical nomenclature.
520			_aThis book is intended for a broad readership, in particular, those working or interested in drug discovery coming from various disciplines such as medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics, and toxicology. It provides, for the first time, a completely integrated look at multiple aspects of ADME sciences (absorption, distribution, metabolism, and excretion) in a summary format that is clear, concise, and self-explanatory. DMPK in Drug Discovery - Guide to Data Interpretation and integration leverages the prior knowledge from the first book that covers the basics of each concept (Drug Metabolism and Pharmacokinetics Quick Guide). This reference book is meant to be used day to day and provides many useful tables (used for data interpretation), figures, and case studies that can facilitate drug discovery. The case studies are intended to be short and relevant to the topic discussed and present another dimension to the discussions.
700	1		_aWong, Harvey _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut
700	1		_aZhang, Donglu _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut
700	1		_aHop, Cornelis E.C.A _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut
776	0	8	_iPrinted edition: _z9783031106903
776	0	8	_iPrinted edition: _z9783031106927
776	0	8	_iPrinted edition: _z9783031106934
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-10691-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
988			_aSpringer_BiomedLife_2022
999			_c394618 _d394618