000			03349nam a22003735i 4500
001			394595
003			ES-MaUEC
005			20230102123142.0
007			cr nn 008mamaa
008			220630s2022 si | s |||| 0|eng d
020			_a9789811910081
024	7		_a10.1007/978-981-19-1008-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aHigh Altitude Sickness - Solutions from Genomics, Proteomics and Antioxidant Interventions _cedited by Narendra Kumar Sharma, Aditya Arya
250			_a1st edition 2022
264		1	_aSingapore _bSpringer International Publishing _c2022
300			_a1 recurso en línea (XI, 223 páginas) _b1 illus
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
505	0		_a1 Introduction to High Altitude and Hypoxia -- 2 High altitude sickness: environmental stressor and altered physiological response -- 3 High-Altitude Related Diseases: Milder Effects, HACE, HAPE, and Effect on Various Organ Systems -- 4 High altitude-induced Oxidative stress, Rheumatoid Arthritis and proteomic alteration -- 5 Oxidative Stress, ROS generation and Associated Molecular Alterations in High Altitude Hypoxia -- 6 Oxidative Stress, ROS generation and Associated Molecular Alterations in High Altitude Hypoxia -- 7 Current problems in diagnosis and treatment of high altitude sickness -- 8 Proteomics as a potential tool for biomarker discovery -- 9 Serum and Plasma Proteomics for High-Altitude Related Biomarker Discovery -- 10 Saliva Proteomics As Non-Invasive Application For Biomarker Studies -- 11 Role of genomics, proteomics and antioxidant interventions in preventing High Altitude Sickness -- 12 High Altitude Sickness And Antioxidant Interventions -- 13 Antioxidant therapy for high altitude sickness and Nano-medicine.
520			_aThis book reviews the recent advances in the development of proteomics-based biomarkers for the non-invasive diagnosis of altitude sickness and explores the potential of antioxidant therapy for this sickness. The first chapters introduce the associated pathophysiology and provide mechanistic insights into the enhanced generation of reactive oxygen and nitrogen species (RONS), which leads to an increase in oxidative damage to lipids, proteins, and DNA. The book then highlights the current problems relating to the diagnosis and treatment of altitude sickness and summarizes novel approaches for identifying potential biomarkers and therapeutics. Lastly, it explores the therapeutic efficacy of antioxidant agents.
700	1		_aSharma, Narendra Kumar _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aArya, Aditya _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9789811910074
776	0	8	_iPrinted edition: _z9789811910098
776	0	8	_iPrinted edition: _z9789811910104
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-19-1008-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
988			_aSpringer_BiomedLife_2022
999			_c394595 _d394595