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020 _a9783031040399
024 7 _a10.1007/978-3-031-04039-9
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aMicrofluidics and Biosensors in Cancer Research
_bApplications in Cancer Modeling and Theranostics
_cedited by David Caballero, Subhas C Kundu, Rui L Reis
250 _a1st edition 2022
264 1 _aCham
_bSpringer International Publishing
_c2022
300 _a1 recurso en línea (XIX, 590 páginas)
_b100 ilustraciones, 99 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aAdvances in Experimental Medicine and Biology
_x2214-8019
_v1379
505 0 _aPart 1. Fundamentals of Microfluidics and Biosensors -- Chapter 1. Fundamentals of Biosensors and Detection Methods -- Chapter 2. How to Get Away with Gradients -- Chapter 3. Sensors and Biosensors in Organs-on-a-chip Platforms -- Chapter 4. Current Trends in Microfluidics and Biosensors for Cancer Research Applications -- Part 2. Modelling the Tumor Microenvironment and Its Dynamic Events -- Chapter 5. The Tumor Microenvironment - an Introduction for the Development of Microfluidic Devices -- Chapter 6. Biomaterials for Mimicking and Modelling Tumor Micro-environment -- Chapter 7. Advancing Tumor Microenvironment Research by Combining Organs-on-chips and Biosensors -- Chapter 8. Microfluidic-driven Biofabrication and the Engineering of Cancer-like Microenvironments -- Chapter 9. Advances in 3d Vascularized Tumor-on-a-chip Technology -- Part 3. Cancer Detection and Diagnosis -- Chapter 10. Biosensors Advances: Contributions to Cancer Diagnostics and Treatment -- Chapter 11. Flexible Sensing Systems for Cancer Diagnostics -- Chapter 12. Coupling Micro-physiological Systems and Biosensors for Improving Cancer Biomarkers Detection -- Chapter 13. Microfluidic Biosensor-based Devices for Rapid Diagnosis and Effective Anti-cancer Therapeutic Monitoring for Breast Cancer Metastasis -- Chapter 14. Liquid Biopsies: Flowing Biomarkers -- Chapter 15. From Exosomes to Circulating Tumor Cells: Using Microfludics to Detect High Predictive Cancer Biomarkers -- Chapter 16. Microfluidics for the Isolation and Detection of Circulating Tumor Cells -- Chapter 17. Evolution in Automatized Detection of Cancer Cells: Advances in Magnetic Microcytometers -- Chapter 18. Droplet-based Microfluidic Chip Design, Fabrication and Use for Ultrahigh-throughput DNA Analysis and Quantification -- Chapter 19. Emerging Microfluidic and Biosensor Technologies for Improved Cancer Theranostics -- Part 4. Clinical Applications: Towards Personalized Medicine -- Chapter 20. Microfluidics for Cancer Biomarker Discovery, Research and Clinical Application -- Chapter 21. Methods for the Detection of Circulating Biomarkers in Cancer Patients -- Chapter 22. Advances in Microfluidics for the Implementation of Liquid Biopsy in Clinical Routine.
520 _aThis book offers a comprehensive overview of the development and application of microfluidics and biosensors in cancer research, in particular, their applications in cancer modeling and theranostics. Over the last decades, considerable effort has been made to develop new technologies to improve the diagnosis and treatment of cancer. Microfluidics has proven to be a powerful tool for manipulating biological fluids with high precision and efficiency and has already been adopted by the pharmaceutical and biotechnology industries. With recent technological advances, particularly biosensors, microfluidic devices have increased their usefulness and importance in oncology and cancer research. The aim of this book is to bring together in a single volume all the knowledge and expertise required for the development and application of microfluidic systems and biosensors in cancer modeling and theranostics. It begins with a detailed introduction to the fundamental aspects of tumor biology, cancer biomarkers, biosensors and microfluidics. With this knowledge in mind, the following sections highlight important advances in developing and applying biosensors and microfluidic devices in cancer research at universities and in the industry. Strategies for identifying and evaluating potent disease biomarkers and developing biosensors and microfluidic devices for their detection are discussed in detail. Finally, the transfer of these technologies into the clinical environment for the diagnosis and treatment of cancer patients will be highlighted. By combining the recent advances made in the development and application of microfluidics and biosensors in cancer research in academia and clinics, this book will be useful literature for readers from a variety of backgrounds. It offers new visions of how this technology can influence daily life in hospitals and companies, improving research methodologies and the prognosis of cancer patients.
700 1 _aCaballero, David
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aKundu, Subhas C
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aReis, Rui L
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783031040382
776 0 8 _iPrinted edition:
_z9783031040405
776 0 8 _iPrinted edition:
_z9783031040412
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-04039-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
988 _aSpringer_BiomedLife_2022
999 _c394560
_d394560