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008			221112s2022 sz | s |||| 0|eng d
020			_a9783031142918
024	7		_a10.1007/978-3-031-14291-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRM852 _b2022 EB
245	0	0	_aRadiopharmaceuticals in the Management of Leptomeningeal Metastasis _cedited by Franklin CL Wong
250			_a1st edition 2022
264		1	_aCham _bSpringer International Publishing, _c2022
300			_a1 recurso en línea (XI, 232 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
505	0		_aHuman Leptomeningeal Metastasis (LM)- Epidemiology and Challenges -- State of Art of LM Radiographic Diagnosis - Anatomic and Functional Imaging -- State of Art of LM Therapies: Intrathecal and Systemic approaches -- Current Practice of Radiation Therapy of LM -- Radionuclides in the Diagnosis and Therapy in Neuro-Oncology -- Radionuclide LM Therapy - Published Clinical Trial Findings -- Intrathecal LM Dosimetry Models- Radionuclides in CSF Spaces -- Human Radiation Dosimetry from Imaging- Guidance for Therapy -- Radiographic Assessment for Monitoring of LM Treatment -- Clinical Assessment for Monitoring of LM Treatment -- Logistic and Regulatory Aspects of Locoregional Radionuclide Therapy -- Radionuclides in the Management of LM- Challenges and Opportunities.
520			_aThis book reviews the current clinical practice of leptomeningeal metastasis (LM) diagnosis and treatment, which is predominately by intrathecal chemotherapy and/or in combination with external beam radiotherapy. LM is a refractory lethal complication of many human malignancies when neoplastic cells grow in the meninges. The use of penetrating emissions from radionuclides has the advantages of visualizing cerebrospinal fluid (CSF) flow and ablating meninges at shallow depths and has been used to diagnose CSF flow anomalies and to treat LM. The scientific bases of using radionuclides inside human CSF and ablating LM will be discussed within the text, with results from established and completed clinical trials to explore optimal use of radionuclides to diagnose and treat LM. Many limitations of current practices of treating LM are also discussed, as well as potential avenues of overcoming these limitations. This book is an ideal guide for clinical researchers in the practice of treating leptomeningeal metastasis including radiologists, neurologists, oncologists and radiotherapists as well as their associates.
988			_aSpringer_Medicine_2022
650		7	_2embne _9141446 _aProductos radiofarmacéuticos
700	1		_aWong, Franklin C.L. _eeditor literario _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783031142901
776	0	8	_iPrinted edition: _z9783031142925
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-14291-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b12/2022 _dz _eh _zSI