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| 003 | ES-MaUEC | ||
| 005 | 20230102123125.0 | ||
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| 008 | 221109s2022 sz | s |||| 0|eng d | ||
| 020 | _a9783031114540 | ||
| 024 | 7 |
_a10.1007/978-3-031-11454-0 _2doi |
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_aES-MaUEC _bspa _cES-MaUEC |
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| 245 | 1 | 0 |
_aDNA Methyltransferases - Role and Function _cedited by Albert Jeltsch, Renata Z Jurkowska |
| 250 | _a2nd edition 2022 | ||
| 264 | 1 |
_aCham _bSpringer International Publishing _c2022 |
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| 300 |
_a1 recurso en línea (IX, 562 páginas) _b1 illus |
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| 336 |
_atexto _btxt _2rdacontent |
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_aelectrónico _bc _2rdamedia |
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_arecurso electrónico _bcr _2rdacarrier |
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_aarchivo de texto _bPDF |
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_aAdvances in Experimental Medicine and Biology _x2214-8019 _v1389 |
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| 505 | 0 | _aChapter 1. Mechanisms and biological roles of DNA methyltransferases and DNA methylation - from past achievements to future challenges -- Chapter 2.Bacterial DNA Methylation and Methylomes -- Chapter 3. ChapterDomain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases -- Chapter 4. Enzymology of Mammalian DNA Methyltransferases -- Chapter 5. Genetic Studies on Mammalian DNA Methyltransferase -- Chapter 6. Structure and Mechanism of Plant DNA Methyltransferases -- Chapter 7. DNA Methylation in Honey Bees and the Unresolved Questions in Insect Methylomics -- Chapter 8. N6-Methyladenine: A Conserved and Dynamic DNA Mark -- Chapter 9. Pathways of DNA Demethylation -- Chapter 10. Structure and Function of TET Enzymes -- Chapter 11.Proteins That Read DNA Methylation -- Chapter 12. Recent advances on DNA base flipping - a general mechanism for writing, reading, and erasing DNA modifications.-Chapter 13. The Role of DNA Methylation in Cancer -- Chapter 14. DNMTs and DNA damage -- Chapter 15. Role of DNMTs in brain -- Chapter 16. Current and Emerging Technologies for the Analysis of the Genome-Wide and Locus-Specific DNA Methylation Patterns.-Chapter 17. Inhibitors of DNA methylation -- Chapter 18. Rewriting DNA Methylation Signatures at Will: The Curable Genome Within Reach? -- Chapter 19. DNA Labeling Using DNA Methyltransferases. | |
| 520 | _aThis 2nd edition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years. As the previous edition, this 2nd edition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA methyltransferase inhibitors and their use in cancer therapy as well as the latest epigenome editing systems based on these enzymes. Overall, this 2nd edition comprehensively summarizes the current state of research in the field of DNA methylation and DNA methyltransferase and is essential reading for early career and advanced researchers in this exciting field. | ||
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_aJeltsch, Albert _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 700 | 1 |
_aJurkowska, Renata Z _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt |
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| 776 | 0 | 8 |
_iPrinted edition: _z9783031114533 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783031114557 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783031114564 |
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_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-11454-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid) |
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| 988 | _aSpringer_BiomedLife_2022 | ||
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_c394379 _d394379 |
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