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001 394201
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008 221018s2022 sz | s |||| 0|eng d
020 _a9783031084911
024 7 _a10.1007/978-3-031-08491-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
245 1 0 _aPseudomonas Aeruginosa :
_bBiology, Pathogenesis and Control Strategies
_cedited by Alain Filloux, Juan-Luis Ramos
250 _a1st edition 2022
264 1 _aCham
_bSpringer International Publishing
_c2022
300 _a1 recurso en línea (XVII, 445 páginas)
_b69 ilustraciones, 55 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aAdvances in Experimental Medicine and Biology
_x2214-8019
_v1386
505 0 _aPart I. Biology and Evolution of Pseudomonas aeruginosa -- Pseudomonas aeruginosa Pangenome: Core and Accessory Genes of a Highly Resourceful Opportunistic Pathogen -- Iron Homeostasis in Pseudomonas aeruginosa: Targeting Iron Acquisition and Storage as an Antimicrobial Strategy -- Controlling Biofilm Development Through Cyclic di-GMP Signaling -- Pseudomonas aeruginosa Quorum Sensing -- Antibiotic Resistance in Pseudomonas -- Part II. Cell Envelope and Secretion Systems -- Cell Envelope Stress Response in Pseudomonas aeruginosa -- Flagella, Chemotaxis and Surface Sensing -- Antimicrobial Weapons of Pseudomonas aeruginosa -- Pseudomonas aeruginosa Antivirulence Strategies: Targeting the Type III Secretion -- Part III. Pathogenesis and Virulence -- What Makes Pseudomonas aeruginosa a Pathogen? -- Transcriptional Profiling of Pseudomonas aeruginosa Infections -- Molecular Mechanisms Involved in Pseudomonas aeruginosa Bacteremia -- Pseudomonas aeruginosa in the Cystic Fibrosis Lung -- Role of Two Component System Networks in Pseudomonas aeruginosa Pathogenesis -- Mixed Populations and Co-Infection: Pseudomonas aeruginosa and Staphylococcus aureus -- How to Manage Pseudomonas aeruginosa Infections.
520 _aThis book covers the wide set of well-regulated virulence factors and defense mechanisms of Pseudomonas aeruginosa focusing on stress responses and the evolution of this opportunistic human pathogen. Pseudomonas aeruginosa is responsible for one out of ten hospital infections. Additionally, this Gram-negative bacterium is accountable for persistent infections in immunocompromised individuals and the leading cause of chronic lung infections in cystic fibrosis patients. This book provides insight on the metabolic versatility of Pseudomonas aeruginosa and its mechanisms for biofilm formation that make this organism highly efficient in causing infections. The book invites the readers to learn more about the intrinsic ability of Pseudomonas aeruginosa to resist a wide variety of antimicrobial agents due to the concerted action of multidrug efflux pumps, antibiotic-degrading enzymes, and the low permeability of bacterial cellular envelopes. Particular focus is put on the evolutionary role of different types of protein-secretion systems in pathogenesis, flagella and their role in chemotaxis and surface sensing, and host-pathogen interactions. This book is a useful introduction to the field for junior scientists interested in the biology and pathogenesis of Pseudomonas aeruginosa. It is also an interesting read for advanced scientists and medical specialists working within this field, providing a broader view of the topic beyond their specific area of specialization.
700 1 _aFilloux, Alain
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRamos, Juan-Luis
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783031084904
776 0 8 _iPrinted edition:
_z9783031084928
776 0 8 _iPrinted edition:
_z9783031084935
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-08491-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
988 _aSpringer_BiomedLife_2022
999 _c394201
_d394201
_x1