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001			394109
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007			cr nn 008mamaa
008			221003s2022 sz | s |||| 0|eng d
020			_a9783031099366
024	7		_a10.1007/978-3-031-09936-6 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aOpioids _bPharmacology, Abuse, and Addiction _cedited by Silvia L Cruz
250			_a1st edition 2022
264		1	_aCham _bSpringer International Publishing _c2022
300			_a1 recurso en línea (XV, 387 páginas) _b36 ilustraciones, 34 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
505	0		_aPart I. Social aspects of opioid use -- Chapter 1: A brief history of opioids and the evolution of concepts associated with substance use disorders -- Chapter 2: The two sides of opioid use: Unmet needs of opioids for pain management and the role of opioids in substance use disorders -- Chapter 3: Opioid markets and special populations -- Chapter 4: Towards a new drug policy agreement -- Chapter 5: The opioid crises -- Chapter 6: Persons who misuse opioids -- Chapter 7: The need for structural interventions for persons who misuse opioids -- Part II. Pharmacological and medical aspects of opioid use -- Chapter 8: Opioid effects and classification -- Chapter 9: Opioid receptors and neuronal signal transduction -- Chapter 10: Opioids in Pain -- Chapter 11: Opioids in Palliative Care -- Chapter 12: Opioids and the immune system -- Chapter 13: Opioid dependence, tolerance, and withdrawal -- Chapter 14: Medication-Assisted Treatment (MAT) 1: Opioid substitution therapy -- Chapter 15: Medication-Assisted Treatment for Opioid Use Disorders 2. Detoxification -- Chapter 16: Synthetic Opioids as New Psychoactive Substances (NPS).
520			_aOpioids are the mainstay in pain treatment and can be invaluable medications in palliative care. However, they are also responsible for the vast majority of preventable deaths related to drug use. This book presents an overview of the social and pharmacological aspects of opioid effects, aiming to provide researchers and health professionals with a firm understanding of their effects and mechanisms of action. The first section reviews the history of opioids from ancient civilizations to the current opioid crisis, gives voice to opioid users through first-hand testimonies, analyzes the existing international drug treatment agreements, and presents structured interventions for persons who misuse opioids. The second section covers state-of-the-art advances in the medical use of opioids, opioid-induced signal transduction, opioids in pain management, opioid use disorders and their treatment. It also presents an updated view of opioids as regulators of inflammation and host defense against pathogens and damage. The overall aim of this book is to provide the reader with a deeper knowledge of this field despite the complexities associated with the existence of numerous ligands, receptor subtypes, and complex pharmacological profiles. To this end, the chapter authors are specialists in the field who also have extensive experience in teaching, hoping to lend their expertise in translating complex concepts into comprehensive and clear explanations.
700	1		_aCruz, Silvia L _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783031099359
776	0	8	_iPrinted edition: _z9783031099373
776	0	8	_iPrinted edition: _z9783031099380
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-09936-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
988			_aSpringer_BiomedLife_2022
999			_c394109 _d394109