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001			393828
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008			220827s2022 sz | s |||| 0|eng d
020			_a9783031054600
024	7		_a10.1007/978-3-031-05460-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
245	1	0	_aUnderstanding PTMs in Neurodegenerative Diseases _cedited by Victor Corasolla Carregari
250			_a1st edition 2022
264		1	_aCham _bSpringer International Publishing _c2022
300			_a1 recurso en línea (VIII, 146 páginas) _b13 ilustraciones, 11 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aProteomics Metabolomics Interactomics and Systems Biology _x2730-6224 _v1382
505	0		_aProtein extraction and sample preparation methods for shotgun proteomics with central nervous system cells and brain tissue -- Phosphopeptide enrichment techniques: a pivotal step for phosphoproteomic studies -- Post-Translational Modifications during Brain Development -- Aberrant protein glycosylation in brain cancers, with emphasis on glioblastoma -- Post-Translational Modification in Muscular Dystrophies -- Post-translational Modifications in Parkinson's Disease -- Histone Modifications in Neurological Disorders -- Mitochondrial dysregulation and the influence in neurodegenerative diseases -- PTMs: A missing piece for schizophrenia studies -- Post-Translational Modifications in Brain Diseases: A Future for Biomarkers -- Index.
520			_aThis new volume, a part of the Proteomics, Metabolomics, Interactomics and Systems Biology series, will explain how proteomic studies of post-translational modifications (PTMs) can be applied to neurodegenerative diseases and relevant studies. The goal of the book is to increase awareness among researchers about how PTMs may be helpful in understanding mechanisms in various neurodegenerative diseases through proteomic studies. This book will serve as a tool for those who want to begin work in the proteomics field and explore how to implement PTMs studies into their work. Chapter authors will describe different PTMs enrichment methods developed by experts in the field so that researchers may learn to apply these methods and techniques to new studies. Divided into three sections, chapters will cover sample preparation, data quality, enrichment techniques, guidelines on how to analyze PTMs, and explain the role of PTMs and different brain diseases. Among those topics includes will be brain cancer, SLA disease, Parkinsons disease, muscular dystrophies, and schizophrenia. This volume will be useful for researchers and students studying brain and neurodegenerative diseases who are interested in delving into work with proteomic studies and PTMs. .
700	1		_aCorasolla Carregari, Victor _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783031054594
776	0	8	_iPrinted edition: _z9783031054617
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-05460-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
988			_aSpringer_BiomedLife_2022
999			_c393828 _d393828