000			05463nam a22003975i 4500
999			_c393725 _d393725 _x1
001			393725
003			ES-MaUEC
005			20240314174421.0
006			a||||fo|||| 00| 0
007			cr nn 008mamaa
008			100301s2009 xxu| o |||| 0|eng d
020			_a9781603275309
024	7		_a10.1007/978-1-60327-530-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC268.48 _b2009 EB
245	0	0	_aInflammation and Cancer : _bMethods and Protocols : Volume 2, Molecular Analysis and Pathways _cedited by Serguei V. Kozlov
250			_a1st edition 2009
264		1	_aTotowa, NJ _bHumana Press _c2009
300			_a1 recurso en línea (XVI, 408 páginas) _b51 ilustraciones
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v512
505	0		_aCrossroads of Inflammation and Cancer: Molecular Aspects -- Immunohistochemical Analysis of 8-Nitroguanine, A Nitrative DNA Lesion, in Relation to Inflammation-Associated Carcinogenesis -- Molecular Analysis of Genetic Instability Caused by Chronic Inflammation -- Obesity Provides a Permissive Milieu in Inflammation-Associated Carcinogenesis: Analysis of Insulin and IGF Pathways -- Detecting and Modulating the NF-kB Activity in Human Immune Cells: Generation of Human Cell Lines with Altered Levels of NF-?B -- Inflammation-Related Aberrant Patterns of DNA Methylation: Detection and Role in Epigenetic Deregulation of Cancer Cell Transcriptome -- cDNA Microarray Analysis of Inflammatory Breast Cancer Signatures -- Analysis of the TLR/NF-?B Pathway in Antigen-Presenting Cells in Malignancies Promoted by Inflammation -- Induced Nitric Oxide Synthase as a Major Player in the Oncogenic Transformation of Inflamed Tissue -- Molecular and Cellular Approaches to Diagnostics and Drug Target Discovery In Inflammation-Related Oncogenesis -- Development of a Cell-Based Assay to Quantify the Inflammatory Potential of Test Substances and Screen Compound Libraries for Anti-cancer Drug Candidates in a High-Throughput Format -- The NF-?B Transcription Factor Pathway as a Therapeutic Target in Cancer: Methods for Detection of NF-?B Activity -- Inhibiting Proinflammatory NF-?B Signaling Using Cell-Penetrating NEMO Binding Domain Peptides -- Quantitative Measurement of Cytokine Expression in Synoviocytes Derived from Rheumatoid Arthritis Patients -- Molecular Characterization of Inflammation-Induced JNK/c-Jun Signaling Pathway in Connection with Tumorigenesis -- Molecular Characterization of STAT Signaling in Inflammation and Tumorigenesis -- Inflammation and Tumor Progression: A Lesson from TNF-?-Dependent FAK Signaling in Cholangiocarcinoma -- Cyclooxygenase Inhibitors Induce Colon Cancer Cell Apoptosis Via PPAR? ? 14-3-3? Pathway -- PPAR?/? Agonist Increases the Expression of PGE2 Receptor Subtype EP4 in Human Lung Carcinoma Cells -- Investigating Macrophage and Malignant Cell Interactions In Vitro -- Cellular Magnetic Resonance Imaging Using Superparamagnetic Anionic Iron Oxide Nanoparticles: Applications to In Vivo Trafficking of Lymphocytes and Cell-Based Anticancer Therapy -- Application of Phage Display to Discovery of Tumor-Specific Homing Peptides: Developing Strategies for Therapy and Molecular Imaging of Cancer -- Molecular Basis of Histone Deacetylase Inhibitors as New Drugs for the Treatment of Inflammatory Diseases and Cancer -- Peptide YY Mediates Inhibition of Tumor Growth and Inflammation.
520			_aAccording to the most recent clinical oncology data, one out of seven newly diagnosed malignancies worldwide result from infection and chronic inflammation in conjunction with cancer. In Inflammation and Cancer: Methods and Protocols, expert researchers deliver a systematic guide to techniques addressing various aspects of experimental cancer biology, selectively focused on inflammation-mediated tumorigenesis, while promoting improvisations on a per-case basis. Volume 2, Molecular Analysis and Pathways is devoted to an extensive description of experimental strategies aimed at investigating the molecular cross-talks between components of cell signaling chains and their ramifications in diagnostic development and drug target discovery. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their subjects, lists of the necessary materials and reagents, step-by-step laboratory protocols, and a notes section, which examines tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Inflammation and Cancer: Methods and Protocols promises to serve as a vital guide and resource for investigators and clinicians working toward the goal of combatting the estimated 2, 200 inflammation-related oncogenesis fatalities occurring every day.
988			_aSpringer_Protocols_2009
650		7	_2embne _9170296 _aCáncer _xEtiología
776	0	8	_iPrinted edition: _z9781607612773
776	0	8	_iPrinted edition: _z9781617379055
776	0	8	_iPrinted edition: _z9781603275293
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60327-530-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2024 _dz _ek _zSI