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020 _a9781493931064
024 7 _a10.1007/978-1-4939-3106-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP551
_b2016 EB
245 0 0 _aStatistical Analysis in Proteomics
_cedited by Klaus Jung
250 _a1st edition 2016
264 1 _aNew York, NY
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (X, 313 páginas)
_b85 ilustraciones, 58 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1362
505 0 _aIntroduction to Proteomics Technologies -- Topics in Study Design and Analysis for Multi-Stage Clinical Proteomics Studies -- Preprocessing and Analysis of LC-MS-Based Proteomic Data -- Normalization of Reverse Phase Protein Microarray Data: Choosing the Best Normalization Analyte -- Outlier Detection for Mass Spectrometric Data -- Visualization and Differential Analysis of Protein Expression Data Using R -- False Discovery Rate Estimation in Proteomics -- A Nonparametric Bayesian Model for Nested Clustering -- Set-Based Test Procedures for the Functional Analysis of Protein Lists from Differential Analysis -- Classification of Samples with Order Restricted Discriminant Rules -- Application of Discriminant Analysis and Cross Validation on Proteomics Data -- Protein Sequence Analysis by Proximities -- Statistical Method for Integrative Platform Analysis: Application to Integration of Proteomic and Microarray Data -- Data Fusion in Metabolomics and Proteomics for Biomarkers Discovery -- Reconstruction of Protein Networks Using Reverse Phase Protein Array Data -- Detection of Unknown Amino Acid Substitutions Using Error-Tolerant Database Search -- Data Analysis Strategies for Protein Modification Identification -- Dissecting the iTRAQ Data Analysis -- Statistical Aspects in Proteomic Biomarker Discovery.
520 _aThis valuable collection aims to provide a collection of frequently used statistical methods in the field of proteomics. Although there is a large overlap between statistical methods for the different 'omics' fields, methods for analyzing data from proteomics experiments need their own specific adaptations. To satisfy that need, Statistical Analysis in Proteomics focuses on the planning of proteomics experiments, the preprocessing and analysis of the data, the integration of proteomics data with other high-throughput data, as well as some special topics. Written for the highly successful Methods in Molecular Biology series, the chapters contain the kind of detail and expert implementation advice that makes for a smooth transition to the laboratory.   Practical and authoritative, Statistical Analysis in Proteomics serves as an ideal reference for statisticians involved in the planning and analysis of proteomics experiments, beginners as well as advanced researchers, and also for biologists, biochemists, and medical researchers who want to learn more about the statistical opportunities in the analysis of proteomics data.
988 _aSpringer_Protocols_2016
650 7 _2embne
_9139861
_aProteínas
776 0 8 _iPrinted edition:
_z9781493931057
776 0 8 _iPrinted edition:
_z9781493931071
776 0 8 _iPrinted edition:
_z9781493979875
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-3106-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b12/2023
_dz
_eb
_zSI