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020 _a9781493969036
024 7 _a10.1007/978-1-4939-6903-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQH450
_b2017 EB
245 0 0 _aPopulation Epigenetics :
_bMethods and Protocols
_cedited by Paul Haggarty, Kristina Harrison
250 _a1st edition 2017
264 1 _aNew York, NY
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (XII, 206 páginas)
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1589
505 0 _aLibrary Construction for High-Throughput Mobile Element Identification and Genotyping -- The Design and Optimization of DNA Methylation Pyrosequencing Assays Targeting Region-Specific Repeat Elements -- Determining Epigenetic Targets: A Beginner's Guide to Identifying Genome Functionality Through Database Analysis -- Detecting Spatial Chromatin Organization by Chromosome Conformation Capture II: Genome-Wide Profiling by Hi-C -- Quantitative Analysis of Intra-chromosomal Contacts: The 3C-qPCR Method -- 5-Hydroxymethylcytosine Profiling in Human DNA -- Adjusting for Cell Type Composition in DNA Methylation Data Using a Regression-Based Approach -- Correcting for Sample Heterogeneity in Methylome-Wide Association Studies -- Nano-MeDIP-seq Methylome Analysis Using Low DNA Concentrations -- Bisulfite Conversion of DNA from Tissues, Cell Lines, Buffy Coat, FFPE Tissues, Microdissected Cells, Swabs, Sputum, Aspirates, Lavages, Effusions, Plasma, Serum, and Urine -- Analysis of Imprinted Gene Regulation -- Statistical Methods for Methylation Data.
520 _aThis detailed volume focuses on population epigenetics, which is of increasing interest to policy makers searching for explanations for complex epidemiological observations and conceptual models on which to base interventions. With a concentration on DNA methylation, the emphasis is on the most commonly studied epigenetic phenomenon that is most amenable to further study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Population Epigenetics: Methods and Protocols aims to aid population researchers in exploiting the latest insights into epigenetics to improve our understanding of the factors that influence human health and longevity.
988 _aSpringer_Protocols_2017
650 7 _2embne
_9526531
_aEpigenética
_vManuales de laboratorio
776 0 8 _iPrinted edition:
_z9781493969012
776 0 8 _iPrinted edition:
_z9781493969029
776 0 8 _iPrinted edition:
_z9781493983339
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-6903-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b12/2023
_dz
_eb
_zSI