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020 _a9781597454230
024 7 _a10.1007/978-1-59745-423-0
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQH442.2
_b2011 EB
245 0 0 _aMethods in Biobanking
_cedited by Joakim Dillner
250 _a1st edition 2011
264 1 _aTotowa, NJ
_bHumana Press
_c2011
300 _a1 recurso en línea (XI, 370 páginas)
_b55 ilustraciones, 4 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v675
505 0 _aGenetic Research and Biobanks -- The Need to Down Regulate: A Minimal Ethical Framework for Biobank Research -- Nordic Biological Specimen Bank Cohorts as Basis for Studies of Cancer Causes and Control: Quality Control Tools for Study Cohorts with More than 2 Million Sample Donors and 100,000 Prospective Cancers -- Biobanks Collected for Routine Healthcare Purposes: Build-Up and Use for Epidemiological Research -- Biobanks and Registers in Epidemiological Research on Cancer -- Study Designs for Biobank-Based Epidemiologic Research on Chronic Diseases -- The EPIC Biobank (European Prospective Investigation into Cancer and Nutrition) -- The AIDS and Cancer Specimen Resource (ACSR) -- Specific Advantages of Twin Registries and Biobanks -- The Swedish Multi-Generation Register -- Multigenerational Information: The Example of the Icelandic Genealogy Database -- Creation of a New Prospective Research Biobank: The Example of HUNT3 -- Best Practices for Establishing a Biobank -- Extraction, Quantitation, and Functionality Evaluation of DNA from Various Sample Types -- Cervical Cytology Biobanks as a Resource for Molecular Epidemiology -- Biobanking of Fresh Frozen Tissue from Clinical Surgical Specimens: Transport Logistics, Sample Selection, and Histological Characterization -- Protein Extraction from Solid Tissue -- Collection and Preservation of Frozen Microorganisms -- Handling of Solid Brain Tumor Tissue for Protein Analysis -- Blood Plasma Handling for Protein Analysis -- Biobank Informatics: Connecting Genotypes and Phenotypes -- A Practical Guide to Constructing and Using Tissue Microarrays -- Breast Cancer Genomics Based on Biobanks -- Monitoring, Alarm, and Data Visualization Service on Sample Preparing and Sample Storing Devices in Biobanks -- Fresh Frozen Tissue: RNA Extraction and Quality Control.
520 _aInternational biobank collaborations allow for studies with large number of subjects where generalizability of findings across populations can be investigated, which means establishing quality criteria concerning the nature of the sample, conditions of sample storage, and the adequacy of available information is of vital importance. Methods in Biobanking brings together contributions from experts in the field in order to aid in the establishment of this much needed consistency. The volume discusses how to use existing collections of biological material to answer significant questions concerning the cause of disease without violating the personal integrity of participating sample donors, the ethical issues surrounding biobanks, guidelines for the use of coding systems and the use of biocomputing and registry linkages in research projects, as well as many other key subjects. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Methods in Biobanking seeks to provide scientists with the tools necessary to take advantage of the tremendous current resources of the world's biobanks and strengthen those resources for the future.
988 _aSpringer_Protocols_2011
650 7 _2embne
_9159969
_aClonación molecular
776 0 8 _iPrinted edition:
_z9781588299956
776 0 8 _iPrinted edition:
_z9781607619062
776 0 8 _iPrinted edition:
_z9781493960774
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-59745-423-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b01/2024
_dz
_eb
_zSI