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999			_c393387 _d393387 _x1
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007			cr nn 008mamaa
008			100301s2006 xxu| fo |||| 0|eng d
020			_a9781597450492
024	7		_a10.1385/1597450499 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQR188.8 _b2006 EB
245	0	0	_aTransplantation Immunology _b: Methods and Protocols _cedited by Philip Hornick
250			_a1st edition 2006
264		1	_aTotowa, NJ _bHumana Press _c2006
300			_a1 recurso en línea (X, 430 páginas) _b54 ilustraciones
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v333
505	0		_aCurrent Status of Renal Transplantation -- Current Status of Liver Transplantation -- Current Status of Clinical Islet Cell Transplantation -- Current Status of Lung Transplantation -- Chronic Rejection in the Heart -- Direct and Indirect Allorecognition -- HLA Typing and Its Influence on Organ Transplantation -- Strategies for Gene Transfer to Solid Organs -- Nonviral Vectors -- Detection and Clinical Relevance of Antibodies After Transplantation -- 11 Reprogramming the Immune System Using Antibodies -- In Vitro Assays for Immune Monitoring in Transplantation -- Proteomics and Laser Microdissection -- Real-Time Quantitative Polymerase Chain Reaction in Cardiac Transplant Research -- Organ Preservation -- Pharmacological Manipulation of the Rejection Response -- Experimental Models of Graft Arteriosclerosis.
520			_aTechnical innovations in the laboratory over the past ten years have greatly improved our understanding of the immunological mechanisms of transplanted organ rejection. In Transplantation Immunology: Methods and Protocols, leading experts in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods of utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The areas of tolerance induction and reprogramming of the immune system are also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection. State of the art and highly practical, Transplantation Immunology: Methods and Protocols illuminates for clinicians and scientists-both newcomers and experts-the new world of detecting and monitoring patients' immunological responses to solid organ transplantation.
988			_aSpringer_Protocols_2006
650		7	_2embne _9336019 _aTrasplante de órganos _xAspectos inmunológicos
776	0	8	_iPrinted edition: _z9781617376320
776	0	8	_iPrinted edition: _z9781588295446
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/1597450499 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2024 _dz _ean _zSI