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008			160413s2016 xxu| fo |||| 0|eng d
020			_a9781493935888
024	7		_a10.1007/978-1-4939-3588-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH671 _b2016 EB
245	0	0	_aApoptosis Methods in Toxicology _cedited by Perpetua M. Muganda
250			_a1st edition 2016
264		1	_aNew York, NY _bSpringer International Publishing _c2016
300			_a1 recurso en línea (X, 244 páginas) _b46 ilustraciones, 35 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Pharmacology and Toxicology _x1940-6053
505	0		_aAn Overview of Apoptosis Methods in Toxicological Research: Recent Updates -- Detection of Apoptosis: From Bench Side to Clinical Practice -- Determining the Extent of Toxicant-Induced Apoptosis Using Concurrent Phased Apoptosis Assays -- Measurement of Apoptosis by Multiparametric Flow Cytometry -- Detecting Apoptosis, Autophagy, and Necrosis -- A Low-Cost Method for Tracking the Induction of Apoptosis Using FRET-Based Activity Sensors in Suspension Cells -- FRET-Based Measurement of Apoptotic Caspase Activities by High-Throughput Screening Flow Cytometry -- Automated Ratio Imaging Using Nuclear-Targeted Fret Probe-Expressing Cells for Apoptosis Detection -- Antibody-Based Proteomic Analysis of Apoptosis Signaling -- Novel Electrochemical Biosensor for Apoptosis Evaluation -- Microplate-Based Whole Zebrafish Caspase 3/7 Assay for Screening Small Molecule Compounds -- Targeting Cancer Cell Death with Small-Molecule Agents for Potential Therapeutics -- Liposomes in Apoptosis Induction and Cancer Therapy.
520			_aThis detailed volume provides a single, valuable reference source for methods that definitively identify and accurately quantify apoptosis. The book begins with common methods utilized to detect and quantitate apoptosis, as well as apoptosis signaling pathways in toxicological and other related research. It continues with multi-parametric and phased apoptosis assays for detecting early and late apoptosis or distinguishing apoptosis from necrosis and autophagy. Subsequent chapters focus on recent advances in real time and high-throughput assays that detect and quantitate apoptosis and apoptosis signaling pathways. Final chapters focus on recent developments in preclinical anticancer therapeutics targeting apoptosis. Written for the Methods in Pharmacology and Toxicology series, chapters feature step-by-step descriptions of the methodologies, as well as expert tips and implementation advice. Vital and authoritative, Apoptosis Methods in Toxicology serves novice scientists as well as experts, utilizing a range of instruments from common laboratory equipment to high-end expensive and automated machinery capable of performing real time apoptotic measurements.
988			_aSpringer_Protocols_2016
650		7	_2embne _9157983 _aApoptosis
776	0	8	_iPrinted edition: _z9781493935864
776	0	8	_iPrinted edition: _z9781493935871
776	0	8	_iPrinted edition: _z9781493980864
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-3588-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2024 _dz _ean _zSI