000			03907nam a22003975i 4500
999			_c393324 _d393324
001			393324
003			ES-MaUEC
005			20240217102643.0
006			a||||fo|||| 00| 0
007			cr nn 008mamaa
008			100301s2000 xxu| fo |||| 0|eng d
020			_a9781592593682
024	7		_a10.1385/1592593682 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP551 _b2000 EB
245	0	0	_aProtein Structure Prediction _b: Methods and Protocols _cedited by David Webster.
250			_a1st edition 2000
264		1	_aTotowa, NJ _bHumana Press _c2000
300			_a1 recurso en línea (430 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v143
505	0		_aMultiple Sequence Alignment -- Protein Structure Comparison Using SAP -- Discovering Patterns Conserved in Sets of Unaligned Protein Sequences -- Identification of Domains from Protein Sequences -- Third Generation Prediction of Secondary Structures -- Comparative Protein Structure Modeling: Introduction and Practical Examples with Modeller -- A Practical Guide to Protein Structure Prediction -- Derivation and Testing Residue-Residue Mean-Force Potentials for Use in Protein Structure Prediction -- Genetic Algorithms and Protein Folding -- Scoring Functions for ab initio Protein Structure Prediction -- Ab Initio Loop Modeling and Its Application to Homology Modeling -- The Dead-End Elimination Theorem: -- Classification of Protein Folds -- Modeling Transmembrane Helix Bundles by Restrained MD Simulations -- Predictive Models of Protein-Active Sites -- Flexible Docking of Peptide Ligands to Proteins -- Geometrical Docking Algorithms: A Practical Approach -- Protein-Protein Docking: Generation and Filtering of Complexes.
520			_aThe deeper understanding of protein structure now emerging from cutting-edge research is not only illuminating evolutionary and biochemical mechanisms, but also promises enormous ramifications for molecular medicine, as well as for biotechnology, biophysics, biology, genetics, and other molecular sciences. In Protein Structure Prediction: Methods and Protocols, world-class investigators detail their most successful methods-and the theory behind them-for delineating the shape, form, and function of proteins. The protocols range from basic to advanced and include sequence alignment, the prediction of transmembrane protein structure, and the development of suitable folding potentials. There are also techniques for receptor site prediction, the identification of motifs and domains, the comparative modeling of proteins, the docking of peptides and ligands, and ab initio approaches to protein loop and side-chain prediction. To ensure robust and successful experimental results, each protocol contains step-by-step instructions, as well as tips on pitfalls to avoid and how procedures may be optimized for different systems. Comprehensive, accessible, and highly practical, Protein Structure Prediction: Methods and Protocols offers protein researchers, structural biologists, and other investigators a critical synthesis of the latest research results, as well as the vital guidance needed to understand the structure and interaction of proteins and peptides.
988			_aSpringer_Protocols_2000
650		7	_2embne _9138424 _aAminoácidos
776	0	8	_iPrinted edition: _z9781489941893
776	0	8	_iPrinted edition: _z9780896036376
776	0	8	_iPrinted edition: _z9781489941886
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/1592593682 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b12/2023 _dz _ean _zSI