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020 _a9781493935154
024 7 _a10.1007/978-1-4939-3515-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 _aRC270.8
_b2016 EB
245 1 0 _aBacterial Therapy of Cancer
_b: Methods and Protocols
_cedited by Robert Hoffman.
250 _a1st edition 2016
264 1 _aNew York, NY
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (XVI, 186 páginas)
_b43 ilustraciones, 33 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1409
505 0 _aTumor Targeting Salmonella Typhimurium A1-R: An Overview -- Enhancement of Tumor-Targeted Delivery of Bacteria with Nitroglycerin Involving Augmentation of the ERP Effect -- Oral Delivery of Tumor-Targeting Salmonella to Treat Cancer in Mice -- Microfluidic Device to Quantify the Behavior of Therapeutic Bacteria in Three-Dimensional Tumor Tissue -- Tumor-Targeting Therapy Using Gene-Engineered Anaerobic-Nonpathogenic Bifidobacterium Longum -- Noninvasive In Vivo Imaging to Follow Bacteria Engaged in Cancer Therapy -- In Vivo Bioluminescence Imaging of Intra-Tumoral Bacteria -- Employment of Salmonella in Cancer Gene Therapy -- Development of a Targeted Gene Delivery System Using Escherichia Coli -- Isolation and Analysis of Suppressor Mutations in Tumor-Targeted msbB Salmonella -- Determination of Plasmid Segregational Stability in a Growing Bacterial Population -- Visualization of Anti-Cancer Salmonella Typhimurium Engineered for Remote-Control of Therapeutic Proteins -- Methods for Tumor Targeting with Salmonella Typhimurium A1-R -- Salmonella Typhimurium A1-R and Cell-Cycle Decoy Therapy of Cancer -- Future of Bacterial Therapy of Cancer.
520 _aThis volume explores the evolution of bacterial cancer therapy and describes the modern techniques used in therapy today. The chapters in this book cover a broad range of topics such as the development of tumor-targeting Salmonella typhimurium A1-R, a microfluidic device for precise quantification of the interactions between tumor-targeting bacteria and tumor tissue, non-invasive in vivo imaging of bacteria-mediated cancer therapy using bio-luminescent bacteria, methods to achieve remote-control of therapeutic gene expression in tumor-targeting bacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs to drug sensitivity by S. typhimurium A1-R. This book concludes with a chapter on the future potential of bacterial therapy of cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and informative, Bacterial Therapy of Cancer: Methods and Protocols is a valuable resource for anyone who is interested in cancer and bacterial therapy.
988 _aSpringer_Protocols_2016
650 7 _2embne
_9174085
_aCáncer
_xTratamiento
776 0 8 _iPrinted edition:
_z9781493935130
776 0 8 _iPrinted edition:
_z9781493935147
776 0 8 _iPrinted edition:
_z9781493980635
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-3515-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b12/2023
_dz
_ean
_zSI