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008			170813s2017 xxua o |||| 0|eng d
020			_a9781493971961
024	7		_a10.1007/978-1-4939-7196-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP90.4 _b2017 EB
245	0	0	_aHemostasis and Thrombosis : _bMethods and Protocols _cedited by Emmanuel J. Favaloro, Giuseppe Lippi
250			_a1st edition 2017
264		1	_aNew York, NY _bSpringer International Publishing _c2017
300			_a1 recurso en línea (XV, 565 páginas) _b93 ilustraciones, 49 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1646
505	0		_aOverview of Hemostasis and Thrombosis and Contribution of Laboratory Testing to Diagnosis and Management of Hemostasis and Thrombosis Disorders -- Preanalytical Issues in Hemostasis and Thrombosis Testing -- The Interface between Immunotransfusion and Hemostasis and Thrombosis Testing -- Optimizing the Verification of Mean Normal Prothrombin Time (MNPT) and International Sensitivity Index (ISI) for Accurate Conversion of Prothrombin Time (PT) to International Normalized Ratio (INR) -- Performance of Activated Partial Thromboplastin Time (APTT): Determining Reagent Sensitivity to Factor Deficiencies, Heparin, and Lupus Anticoagulants -- Performance and Interpretation of Mixing Tests in Coagulation -- D-Dimer Testing: Laboratory Aspects and Current Issues -- Determination of Fibrinogen and Thrombin Time (TT) -- An Overview of Thrombophilia and Associated Laboratory Testing -- Laboratory Testing for Activated Protein C Resistance (APCR) -- Assessment of Hereditary Thrombophilia: Performance of Protein C (PC) Testing -- Assessment of Hereditary Thrombophilia: Performance of Protein S (PS) Testing -- Assessment of Hereditary Thrombophilia: Performance of Antithrombin (AT) Testing -- Lupus Anticoagulant Testing: Diluted Russell Viper Venom Time (dRVVT) -- Lupus Anticoagulant Testing: Activated Partial Thromboplastin Time (APTT) and Silica Clotting Time (SCT) -- Solid Phase Immunoassay for the Detection of Anticardiolipin Antibodies -- Solid Phase Immunoassay for the Detection of Anti-β2 Glycoprotein I Antibodies -- Measuring Direct Oral Anticoagulants -- Laboratory Testing Protocols for Heparin-Induced Thrombocytopenia (HIT) Testing -- One-Stage Factor VIII Assays -- Chromogenic Factor VIII Assays for Improved Diagnosis of Hemophilia A -- Assessment of Factor XIII -- Detection and Measurement of Factor Inhibitors -- Platelet Function Tests: Preanalytical Variables, Clinical Utility, Advantages and Disadvantages -- Platelet Function Analyzed by Light Transmission Aggregometry -- Whole Blood Platelet Aggregometry -- Assessment of Platelet Function in Whole Blood by Flow Cytometry -- Flow Cytometry Protocols for Assessment of Platelet Function in Whole Blood -- Diagnosis or Exclusion of Von Willebrand Disease Using Laboratory Testing -- Laboratory Testing for Von Willebrand Factor Antigen (VWF:Ag) -- Laboratory Testing for Von Willebrand Factor Collagen Binding (VWF:CB) -- Laboratory Testing for Von Willebrand Factor Ristocetin Cofactor (VWF:RCo) -- Laboratory Testing for Von Willebrand Factor Activity by Glycoprotein Ib Binding Assays (VWF:GPIb) -- Laboratory Testing for Von Willebrand Factor Factor VIII Binding (for 2N VWD) -- Ristocetin-Induced Platelet Aggregation (RIPA) and RIPA Mixing Studies -- Laboratory Testing for Von Willebrand Factor Multimers -- Thrombin Generation Assays (TGA) -- The Overall Haemostatic Potential (OHP) Assay -- Thromboelastography (TEG) -- Post-Analytical Issues in Hemostasis and Thrombosis Testing.
520			_aThis collection thoroughly explores the dynamic and ever-developing field of hemostasis and thrombosis diagnostics and research. After an introductory section covering the basics and preanalytical issues, the book continues with in-depth sections that explore how to get the best outcomes from routine coagulation and specialized hemostasis assays, thrombophilia-related techniques, investigations into bleeding disorders, as well as performance of global assays of hemostasis, and finally post-analytical issues in hemostasis and thrombosis testing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Comprehensive and practical, Hemostasis and Thrombosis: Methods and Protocols serves as an ideal resource for researchers and diagnostic laboratories seeking expert guidance and working to identify the best methodologies to pursue hemostasis and thrombosis testing.
988			_aSpringer_Protocols_2017
650		7	_2embne _9144968 _aHomeostasis _vManuales de laboratorio
650		7	_2embne _9140382 _aTrombosis _vManuales de laboratorio
776	0	8	_iPrinted edition: _z9781493971947
776	0	8	_iPrinted edition: _z9781493971954
776	0	8	_iPrinted edition: _z9781493984138
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7196-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2024 _dz _eb _zSI