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020 _a9781493935604
024 7 _a10.1007/978-1-4939-3560-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC349.8
_b2016 EB
245 0 0 _aImmunotherapy and Biomarkers in Neurodegenerative Disorders
_cedited by Martin Ingelsson, Lars Lannfelt
250 _a1st edition 2016
264 1 _aNew York, NY
_bSpringer International Publishing
_c2016
300 _a1 recurso en línea (X, 289 páginas)
_b40 ilustraciones, 32 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Pharmacology and Toxicology
_x1940-6053
505 0 _aImmunotherapy Against Amyloid-β in Alzheimer's Disease: An Overview -- Active Immunization Against the Amyloid-β Peptide -- Immunotherapy Against N-Truncated Amyloid-β Oligomers -- Immunotherapy Against Amyloid-β Protofibrils: Opportunities and Challenges -- Immunotherapy Against α-Synuclein Pathology -- Extracellular α-Synuclein as a Target for Immunotherapy -- Immunotherapy of Parkinson's Disease -- Tau Immunotherapy -- Active and Passive Immunotherapy Against Tau: Effects and Potential Mechanisms -- Immunotherapy on Experimental Models for Huntington's Disease -- Cerebrospinal Fluid Biomarkers in Alzheimer's Disease -- Volumetric MRI as a Diagnostic Tool in Alzheimer's Disease -- PET Imaging as a Diagnostic Tool in Alzheimer´s Disease -- Αlpha-Synuclein as a Diagnostic Biomarker for Parkinson's Disease -- Imaging as a Diagnostic Tool in Parkinson's Disease -- Mass Spectrometry-Based Proteomics in Biomarker Discovery for Neurodegenerative Diseases.
520 _aThis practical volume examines a number of topics that explore the current status of immunotherapy and diagnostic markers for neurodegenerative disorders. With a focus on Alzheimer's disease, the first sections of the book examine immunotherapeutic approaches for the aforementioned disease as well as for Parkinson's disease and Huntington's disease, amongst others. The last section of the book covers the importance of biomarker techniques to catch these diseases early enough for the treatments to be most useful. Written for the Methods in Pharmacology and Toxicology series, this book contains the kind of detailed descriptions and implementation advice that will offer a smooth transition into the lab. Authoritative and useful, Immunotherapy and Biomarkers in Neurodegenerative Disorders aims to aid in the continued progress in the development of novel immune-based drugs and diagnostic tools for these devastating brain diseases.
988 _aSpringer_Protocols_2016
650 7 _2embne
_9176383
_aSistema nervioso
_xEnfermedades
_xTratamiento
776 0 8 _iPrinted edition:
_z9781493935581
776 0 8 _iPrinted edition:
_z9781493935598
776 0 8 _iPrinted edition:
_z9781493980789
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-3560-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b01/2024
_dz
_eb
_zSI