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020 _a9781627035446
024 7 _a10.1007/978-1-62703-544-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQD431.25 .S93
_b2013 EB
245 0 0 _aPeptide Synthesis and Applications
_cedited by Knud J. Jensen, Pernille Tofteng Shelton, Søren L. Pedersen
250 _a2nd edition 2013
264 1 _aTotowa, NJ
_bHumana Press
_c2013
300 _a1 recurso en línea (X, 253 páginas)
_b68 ilustraciones
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1047
505 0 _aSolid-Phase Peptide Synthesis: An Introduction -- Linkers, Resins and General Procedures for Solid-phase Peptide Synthesis -- Peptide Release, Side-chain Deprotection, Work-up, and Isolation -- Synthesis of Peptides using Tert-butyloxycarbonyl (Boc) as the α-amino Protection Group -- Sequential Formation of Regioselective Disulfide Bonds in Synthetic Peptides with Multiple Disulfide Bonds -- Synthesis of Cyclic Disulfide-Rich Peptides -- Preparation of C-terminally Modified Chemokines by Expressed Protein Ligation -- Synthesis of C-terminal Peptide Thioesters using Fmoc Based Solid-phase Peptide Chemistry -- Backbone Amide Linker Strategy -Protocols for the Synthesis of C‑terminal Peptide Aldehydes -- Synthesis of N-methylated Peptides: On-resin Methylation and Microwave-Assisted Couplings -- Synthesis of Antimicrobial Peptoids -- Synthesis of Lipidated Peptides -- Solid-Phase Synthesis of Phosphopeptides -- Synthesis of O-Glycopeptides and Construction of Glycopeptide Microarrays -- Instruments for Automated Peptide Synthesis -- Microwave-Assisted Solid-Phase Peptide Synthesis using the Biotage Syro Wave™ -- Microwave-Assisted Solid-Phase Peptide Synthesis Based on the Fmoc Protecting Group Strategy (CEM).
520 _aPeptides are used ubiquitously for studies in biology, biochemistry, chemical biology, peptide based medicinal chemistry, and many other areas of research. There is a number of marketed peptide drugs, and the prospects for the development of new peptide drugs are very encouraging.  The second edition of  Peptide Synthesis and Applications expands upon the previous editions with current, detailed methodologies for peptide synthesis. With new chapters on laboratory protocols for both the specialist and the non-specialist. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Peptide Synthesis and Application, Second Edition seeks to aid scientists in understanding different approaches to the synthesis of peptides by using a broad range of methods and strategies.
988 _aSpringer_Protocols_2013
650 7 _2embne
_9146243
_aPéptidos
_xSíntesis
776 0 8 _iPrinted edition:
_z9781627035453
776 0 8 _iPrinted edition:
_z9781627035439
776 0 8 _iPrinted edition:
_z9781493960040
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-62703-544-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b01/2024
_dz
_eb
_zSI