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008			141111s2015 xxua o |||| 0|eng d
020			_a9781493915682
024	7		_a10.1007/978-1-4939-1568-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQM563 _b2015 EB
245	0	0	_aMast Cells : _bMethods and Protocols _cedited by Michael R. Hughes, Kelly M. McNagny
250			_a2nd edition 2015
264		1	_aNew York, NY _bSpringer International Publishing _c2015
300			_a1 recurso en línea (XVII, 540 páginas) _b64 ilustraciones, 46 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1220
505	0		_aPaul Ehrich's Mastzellen:  A Historical Perspective of Relevant Developments in Mast Cell Biology -- The Phylogenetic Profile of Mast Cells -- Mast Cell Development and Function in the Zebrafish -- Human Mast Cell and Basophil/Eosinophil Progenitors -- Methods for the Study of Mast Cell Recruitment and Accumulation in Different Tissues -- Notch2 Signaling in Mast-cell Development & Distribution in the Intestine -- Mast Cells in Human Health and Disease -- The Emerging Prominence of the Cardiac Mast Cell as a Potent Mediator of Adverse Myocardial Remodeling -- The Parasympathetic Nervous System as a Regulator of Mast Cell Function --  Growth of Human Mast Cells from Bone Marrow and Peripheral Blood-Derived CD34+ Pluripotent Hematopoietic Cells -- Isolation and Characterization of Human Intestinal Mast Cells -- Human Mast Cell Activation with Viruses and Pathogen Products -- Basic Techniques to Study FceRI Signaling in Mast Cells -- Membrane-cytoskeleton Dynamics in the Course of Mast Cell Activation -- FcεRI Expression and Dynamics on Mast Cells -- Regulation of Mast Cell Survival and Apoptosis -- Protein Tyrosine Phosphatases in Mast Cell Signaling -- MicroRNA Function in Mast Cell Biology:Protocols to Characterize and Modulate microRNA Expression -- Assay of Mast Cell Mediators -- Induction Of Mast Cell Apoptosis By A Novel Secretory Granule-Mediated Pathway -- Measurement of Nitric Oxide in Mast Cells with the Fluorescent Indicator DAF-FM Diacetate -- Real-time Imaging of Ca2+ Mobilization and Degranulation in Mast Cells -- Flow Cytometry-based Monitoring of Mast Cell Activation -- Measurement of Mast Cell Surface Molecules using High-throughput Immunophenotyping using Transcription (HIT) -- Investigatiotion using Novel Mouse Models of Mast Cell Deficiency and Mast Cell-specific Gene Inactivation -- Evaluation of Synovial Mast Cell Functions in Autoimmune Arthritis -- Methods for the Study of Mast Cells in Cancer -- Studying Mast Cells in Peripheral Tolerance by using a Skin Transplantation Model -- The Function of Mast Cells in Autoimmune Glomerulonephritis -- A Mouse Model of Atopic Dermatitis -- Mouse Models of Allergic Asthma -- Methods in Assessment of Airway Reactivity in Mice.
520			_aMast Cells: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed reviews that cover topics of interest to mast cell neophytes and cognoscenti alike.  With new chapters on methods for the enumeration of tissue mast cells and isolation of mature mast cells and mast cell progenitors from mammalian tissues, Danio rerio (zebrafish) model in the study of mast cell development and function, the functions of mast cells in human health and disease and methods for the isolation, methods for the investigation of the molecular mechanisms of mast cell activation and their effector functions, assays for the detection and analysis of mast cell secretory and cell surface phenotype and, mast cell activation state, and experimental mouse models of disease that have been deemed useful for the assessment of mast cell functions in the regulation of innate and adaptive immune response in cancer, tissue fibrosis, auto-inflammation and allergic disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mast Cells: Methods and Protocols, Second Edition provides a sampler of useful methods and techniques in the further study of mast cell biology.
988			_aSpringer_Protocols_2015
650		7	_2embne _9668820 _aTejido conjuntivo _vManuales de laboratorio
776	0	8	_iPrinted edition: _z9781493915675
776	0	8	_iPrinted edition: _z9781493915699
776	0	8	_iPrinted edition: _z9781493951703
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-1568-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2024 _dz _eb _zSI