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020 _a9781493967506
024 7 _a10.1007/978-1-4939-6750-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQH440.5
_b2017 EB
245 0 0 _aHaplotyping :
_bMethods and Protocols
_cedited by Irene Tiemann-Boege, Andrea Betancourt
250 _a1st edition 2017
264 1 _aNew York, NY
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (X, 326 páginas)
_b54 ilustraciones, 37 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1551
505 0 _aHaplotyping of Heterozygous SNPs in Genomic DNA using Long Range PCR -- Quantification and Sequencing of Crossover Recombinant Molecules from Arabidopsis Pollen DNA -- Pacbio for Haplotyping in Gene Families- High Molecular Weight DNA Enrichment with Peptide Nucleic Acid Probes -- High-Throughput Sequencing of the Major Histocompatibility Complex following Targeted Sequence Capture -- Pedigree-defined Haplotypes and their Applications to Genetic Studies -- Haplotyping a Non-Meiotic Diploid Fungal Pathogen using Induced Aneuploidies and SNP/CGH Microarray Analysis -- Whole-genome Haplotyping of Single Sperm of Daphnia Pulex (Crustacea, Anomopoda) -- Chromosome-range Whole-genome High-throughput Experimental Haplotyping by single-chromosome Microdissection -- Phased Genome Sequencing through Chromosome Sorting -- Long Fragment Read (LFR) Technology: Cost-effective, High-quality Genome-wide Molecular Haplotyping -- Contiguity-Preserving Transposition Sequencing (CPT-seq) for Genome-Wide Haplotyping, Assembly, and Single-Cell ATAC-seq -- Fosmid Pool-Based Next Generation Sequencing to Haplotype-Resolve Whole Genomes -- Discovery of Rare-haplotype Variants by Typing Millions of Single-molecules with Bead Emulsion Haplotyping (BEH) -- Computational Haplotype Inference from Pooled Samples.
520 _aThis volume details protocols for genetic, molecular, cytological, and bioinformatic methods for determining haplotypes. Haplotyping: Methods and Protocols guides readers through methods that directly type haploid cells, difficult-to-resolve gene families, high-resolution, short range haplotyping for targeted loci, and long-range haplotyping for whole chromosomes or genomes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical Haplotyping: Methods and Protocols, aims to provide researchers with an overview of experimental methods for haplotyping.
988 _aSpringer_Protocols_2017
650 7 _2embne
_9138044
_aGenética
_vManuales de laboratorio
776 0 8 _iPrinted edition:
_z9781493967483
776 0 8 _iPrinted edition:
_z9781493967490
776 0 8 _iPrinted edition:
_z9781493982912
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-6750-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b12/2023
_dz
_eb
_zSI