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008			100301s1996 xxua o |||| 0|eng d
020			_a9781592595907
024	7		_a10.1385/0896033414 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC270 _b1996 EB
245	0	0	_aMolecular Diagnosis of Cancer _cedited by Finbarr Cotter
250			_a1st edition 1996
264		1	_aTotowa, NJ _bHumana Press _c1996
300			_a1 recurso en línea (XIV, 218 páginas) _b41 ilustraciones, 8 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Medicine _x1940-6037 _v6
505	0		_aHematological Malignancies -- PCR of Gene Rearrangements for the Detection of Minimal Residual Disease in Childhood ALL -- Detection of BCR-ABL in Hematological Malignancies by RT-PCR -- Molecular Diagnosis of Acute Myeloid Leukemia with Maturation, FAB-Type M2 -- Analysis of the PML/RAR-? Fusion Gene in Acute Promyelocytic Leukemia by Reverse-Transcription Polymerase Chain Reaction -- RT-PCR Analysis of Breakpoints Involving the MLL Gene Located at 11q23 in Acute Leukemia -- Polymerase Chain Reaction for Detection of the t(14;18) Translocation in Lymphomas -- NPM-ALK Reverse Transcriptase-Polymerase Chain Reaction Analysis for Detection of the t(2;5) Translocation of Non-Hodgkin's Lymphoma -- Molecular Diagnosis of the 5q Deletion in Malignant Myeloid Disorders -- Polymerase Chain Reaction Based Methods for Assessing Chimerism Following Allogeneic Bone Marrow Transplantation -- Solid Tumors -- Identification of Mutations in the Retinoblastoma Gene -- Mutational Analysis of the Wilms' Tumor (WTI) Gene -- General Techniques for Cancer Analysis -- Single-Strand Conformation Polymorphism Mutation Analysis of the p53 Gene -- The Characterization of Chromosomal Abnormalities Using Fluorescence In SituHybridization Procedures -- Comparative Genomic Hybridization -- In Situ Hybridization of Cells and Tissue Sections -- Apoptosis Detection by DNA Analysis.
520			_aThe aims of Molecular Diagnosis of Cancer are to introduce scientists and physicians working in the field of diagnostics to the area of cancer molecular pathology and to highlight the possibilities of its application to the cancer physician in the clinic. The degree of molecular biological expertise required should be minimal, although those with more experience may also be able to benefit from the book. All of the authors have considerable practical experience in the method they describe and are working predominantly in the setting of the cancer clinic. As such, the book pulls together a number of te- niques that are already being applied to a wide range of malignancies. Mo- over, this field will continue to expand exponentially as further research leads to a greater understanding of the molecular basis of cancer. Detection of the changes to the DNA or RNA code within a diseased cell often provides pathological information for the diagnosis, prognosis, and m- agement of the disease. Such DNA-related analysis is primarily the role of molecular pathology. Methods to detect these alterations are being refined and are evolving from the research to the diagnostic laboratory. One of the single most powerful techniques in this new branch of pathology has been the polymerase chain reaction (PCR), to which much of this book is devoted.
988			_aSpringer_Protocols_1996
650		7	_2embne _9182544 _aCáncer _xDiagnóstico
776	0	8	_iPrinted edition: _z9781489940315
776	0	8	_iPrinted edition: _z9780896033412
776	0	8	_iPrinted edition: _z9781489940308
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/0896033414 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b12/2023 _dz _eb _zSI