000			04080nam a22003975i 4500
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003			ES-MaUEC
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006			a||||fo|||| 00| 0
007			cr nn 008mamaa
008			121116s2013 xxu| fo |||| 0|eng d
020			_a9781627032094
024	7		_a10.1007/978-1-62703-209-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC280 .B7 _b2013 EB
245	0	0	_aAnimal Models of Brain Tumors _cedited by Ricardo Martínez Murillo, Alfredo Martínez
250			_a1st edition 2013
264		1	_aTotowa, NJ _bHumana Press _c2013
300			_a1 recurso en línea (XIII, 391 páginas) _b66 ilustraciones, 43 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNeuromethods _x1940-6045 _v77
505	0		_aBrain Tumor Models to Predict Clinical Outcome: Like the Phoenix? -- Animal Models in Cancer Research: Assessment of Severity and the Application of Humane Endpoints -- The VM Mouse Model of Glioblastoma Multiforme -- Oligodendroglioma Models -- Medulloblastoma Model -- Learning about Retinoblastoma from Mouse Models that Missed -- Ependymoma Models -- Meningioma Models -- Pituitary Models -- Growth Regulation of Nervous System Tumors: Models for Assessment of Angiogenesis in Brain Tumors -- Using Genetically-Engineered Mouse Models to Understand Low-Grade Glioma Development and Growth in Children -- EGFR and Tumor-Suppressor Function in Brain Cancer Development -- Rodent Glioma Models: Intracranial Stereotactic Allografts and Xenografts -- Immunotherapy of High-Grade Gliomas: Preclinical In Vivo Experiments in Animal Models -- Assessing Mechanisms of Glioblastoma Invasion -- Positron Emission Tomography (PET)-Based Molecular Imaging -- In Vivo Magnetic Resonance Spectroscopic Imaging (MRSI) and Ex Vivo Quantitative Neuropathology by High Resolution Magic Angle Spinning Proton Magnetic Resonance Spectroscopy (HRMAS)- Single Photon Emission Computed Tomography (SPECT) in Small Animal CNS Research.
520			_aAlthough the available models, whether at the cellular, tissue, or animal level, do not exactly represent the biology of human brain tumors, animal models can offer significant insights into these tumors, providing a better understanding of biological mechanisms underlying tumor generation, growth, angiogenesis, invasion, and metastasis.  Animal Models of Brain Tumors brings together developments and discoveries in "in vivo" experimental tumor research that have provided advances in our understanding of the cellular and molecular mechanisms involved in the generation, progression, and clinical outcome of brain neoplasms. Broken into convenient sections, this thorough volume includes topics such as animal model insights into human brain neoplasms, the cellular, molecular, and genetic basis of brain tumors,  therapies in the treatment of malignant glioma, as well as imaging technologies in animal tumor models, i.e. measuring brain tumor growth and metabolism.  Written for the popular Neuromethods series, chapters include the kind of detailed description and implementation advice that is essential for achieving successful results.   Authoritative and cutting-edge, Animal Models of Brain Tumors provides the key methods needed to validate, compare, and contrast the animal model with its proposed human counterpart and further the understanding of our own serious ailments.
988			_aSpringer_Protocols_2013
650		7	_2embne _9138374 _aEnfermedades _xModelos
776	0	8	_iPrinted edition: _z9781627032087
776	0	8	_iPrinted edition: _z9781627032100
776	0	8	_iPrinted edition: _z9781493958948
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-62703-209-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b12/2023 _dz _ean _zSI