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020 _a9781493918720
024 7 _a10.1007/978-1-4939-1872-0
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP519.9 .M3
_b2015 EB
245 0 0 _aClinical Proteomics
_bMethods and Protocols
_cedited by Antonia Vlahou, Manousos Makridakis
250 _a2nd edition 2015
264 1 _aNew York, NY
_bSpringer International Publishing
_c2015
300 _a1 recurso en línea (XIII, 278 páginas)
_b40 ilustraciones, 28 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1243
505 0 _aBiological Sample Collection For Clinical Proteomics - Existing SOPs -- Targeting The Proteome Of Cellular Fractions: Focus on Secretome -- Preparation Of Urinary Exosomes: Methodological Issues For Clinical Proteomics -- Sample Treatment Methods Involving Combinatorial Peptide Ligand Libraries For Improved Proteomes Analyses -- Glycoprotein Enrichment Method Using A Selective Magnetic Nano-Probe Platform (MNP) Functionalized With Lectins -- The Latest Advancements In Proteomic Two-Dimensional Gel Electrophoresis Analysis Applied To Biological Samples -- 2DE Maps In The Discovery Of Human Autoimmune Kidney Diseases: The Case of Membranous Glomerulonephritis -- MALDI-Imaging Mass Spectrometry on Tissues -- Laser Capture Microdissection Of Fluorescently Labeled Amyloid Plaques From Alzheimer's Disease Brain Tissue For Mass Spectrometric Analysis -- Urine Sample Preparation And Fractionation For Global Proteome Profiling By LC-MS -- Methods In Capillary Electrophoresis Coupled To Mass Spectrometry For The Identification Of Clinical Proteomic/Peptidomic Biomarkers In Biofluids -- Quantification Of Proteins In Urine Samples Using Targeted Mass Spectrometry Methods -- Statistical Issues In The Design And Planning Of Proteomic Profiling Experiments -- Integrating Proteomics Profiling Data Sets - A Network Perspective -- The European Medicines Agency Experience With Biomarker Qualification.
520 _aThis second edition expands upon the previous edition with current, detailed developments in the field and brings together a multi-disciplinary team of leading researchers to provide their latest protocols for clinical proteomics analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Authoritative and Practical, Clinical Proteomics: Methods and Protocols, Second Edition presents  approaches that will serve as a reliable guide to researchers, including clinicians, chemists, molecular biologists, bioinformaticians and computational, biologists, and investigators working on biomarker development.
988 _aSpringer_Protocols_2015
650 7 _2embne
_9141447
_aEspectrometría de masas
776 0 8 _iPrinted edition:
_z9781493918737
776 0 8 _iPrinted edition:
_z9781493918713
776 0 8 _iPrinted edition:
_z9781493947294
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-1872-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b11/2023
_dz
_ean
_zSI