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008			131004s2014 xxu| fo |||| 0|eng d
020			_a9781461482444
024	7		_a10.1007/978-1-4614-8244-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC269.5 _b2014 EB
245	0	0	_aMetastasis Research Protocols _cedited by Miriam Dwek, Udo Schumacher, Susan A. Brooks
250			_a2nd edition 2014
264		1	_aNew York, NY _bSpringer International Publishing _c2014
300			_a1 recurso en línea (XI, 250 páginas) _b34 ilustraciones, 10 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1070
505	0		_aIn Vitro Invasion Assay Using MatrigelTM - a  Reconstituted Basement Membrane Preparation -- Single Cell and Spheroid Collagen Type I Invasion Assay -- Rocking Adhesion Assay System to Study Adhesion and Transendothelial Migration of Cancer Cells -- Small Cell Lung Cancer (SCLC) Cell Adhesion on E- and P-Selectin under Physiological Flow Conditions -- Adhesion of Tumour Cells to Matrices and Endothelium -- Cell Aggregation Assays -- Chick Heart Invasion Assay -- Computer Simulation of the Metastatic Progression -- Theoretical Considerations In Using Animal Models of Metastasis and Brief Methodology for In Vivo Colorectal Cancer Models in SCID and Nude Mice -- Syngeneic Murine Metastasis Models: B16 Melanoma -- Imageable Clinically-relevant Mouse Models of Metastasis -- Imaging Metastatic Cell Trafficking at the Cellular Level in vivo with Fluorescent Proteins -- Ultrasound Techniques for the Detection of Tumours and Metastases in Small Animals -- The PFP/RAG2 Double Knock Out Mouse in Metastasis Research: Small Cell Lung Cancer and Prostate Cancer -- Ultrasound Guided Intracardial Injection and In-vivo Magnetic Resonance Imaging of Single Cells in Mice as a Paradigm for Haematogenous Metastases -- Magnetic Resonance Imaging of Metastases in Xenograft Mouse Models of Cancer -- Spontaneous and Experimental Metastasis Models: Nude Mice -- Identifying the Origin and Phenotype of Cells in Tumour Xenografts.
520			_aThe second edition of Metastasis Research Protocols brings together updated versions of the seminal technique that were presented in the first edition and also includes new techniques that have recently been shown to be important in illuminating the processes underlying this important area of biology. Volume 2 presents techniques applicable at the level of living cells and tissues, and presents methodologies applicable to cell behaviour in vitro, in animal models and in mathematical constructs. The aim is the study of  the interaction between cancer cells and their host/environment. The focus throughout is on the tools that have been shown to be helpful in unravelling the processes important in cancer metastasis.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Metastasis Research Protocols, Second Edition: Volume 2 seeks to aid scientists in the further study of new methods in the area of metastasis research.
988			_aSpringer_Protocols_2014
650		7	_2embne _9413460 _aMetástasis
776	0	8	_iPrinted edition: _z9781461482451
776	0	8	_iPrinted edition: _z9781461482437
776	0	8	_iPrinted edition: _z9781493948871
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4614-8244-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b11/2023 _dz _ean _zSI