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008			150123s2015 xxu| o |||| 0|eng d
020			_a9781493920204
024	7		_a10.1007/978-1-4939-2020-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRS431 .P38 _b2015 EB
245	0	0	_aPeptide Libraries : _bMethods and Protocols _cedited by Ratmir Derda
250			_a1st edition 2015
264		1	_aNew York, NY _bSpringer International Publishing _c2015
300			_a1 recurso en línea (XVII, 278 páginas) _b87 ilustraciones, 42 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1248
505	0		_aDesign, Synthesis and Application of OB2C Combinatorial Peptide and Peptidomimetic Libraries -- Synthesis of Macrocyclic Organo-Peptide Hybrids from Ribosomal Polypeptide Precursors via CuAAC-/Hydrazide-Mediated Cyclization -- Synthesis and Screening of One-Bead-One-Compound Cyclic Peptide Libraries -- Creating Site-Specific Isopeptide Linkages Between Proteins with the Traceless Staudinger Ligation -- Macrocyclic Templates for Library Synthesis of Peptido-Conjugates -- Synthesis and Alkylation of aza-Gly-Pro Building Blocks of Peptidomimetic Libraries for Developing Prostaglandin F2α Receptor Modulators as Therapeutics to Inhibit Preterm Labour -- A Fragment Based Selection Approach for the Discovery of Peptide Macrocycles Targeting Protein Kinases -- Peptide and Peptide Library Cyclization Via Bromomethyl Benzene Derivatives -- Phage Selection of Bicyclic Peptides Based on Two Disulfide Bridges -- De Novo Discovery of Bioactive Cyclic Peptides Using Bacterial Display and Flow Cytometry -- Chemical Post-Translational Modification of Phage-Displayed Peptides -- Mapping Protein-Protein Interactions with Phage-Displayed Combinatorial Peptide Libraries and Alanine-Scanning -- Identifying Reactive Peptides from Phage-Displayed Libraries -- The Best and the Brightest: Exploiting Tryptophan-Sensitized Tb3+ Luminescence to Engineer Lanthanide-Binding Tags -- Synthesis and Cell-Based Screening of One-Bead One-Compound Peptide Libraries -- Screening Peptide Array Library for the Identification of Cancer Cell Binding Peptides -- Next Generation Sequencing of Phage-Displayed Peptide Libraries -- Maleimide-Based Method for Elaboration of Cysteine-Containing Peptide Phage Libraries.
520			_aThis volume provides an overview of modern and emerging methods for production, analysis,  and utility of peptide libraries. Chapter focus on methods and techniques for synthesis, genetic expression, hybrid synthesis-expression, examples of modern utility of these libraries, de novo discovery of reactions,  hybrid organic-inorganic materials and, emerging tools for the analysis of these libraries by method of genetic selection and next-generation sequencing. Written in the highly successful Methods in Molecular Biology  series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Peptide Libraries: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies.
988			_aSpringer_Protocols_2015
650		7	_2embne _9146243 _aPéptidos
776	0	8	_iPrinted edition: _z9781493920211
776	0	8	_iPrinted edition: _z9781493920198
776	0	8	_iPrinted edition: _z9781493946426
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-2020-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2024 _dz _eIG _zSI