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008			140123s2014 xxu| 0 |||| 0|eng d
020			_a9781627037853
024	7		_a10.1007/978-1-62703-785-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP383.12 _b2014 EB
245	0	0	_aOptical Imaging of Neocortical Dynamics _cedited by Bruno Weber, Fritjof Helmchen
250			_a1st edition 2014
264		1	_aTotowa, NJ _bHumana Press _c2014
300			_a1 recurso en línea (XII, 296 páginas) _b73 ilustraciones, 70 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNeuromethods _x1940-6045 _v85
505	0		_aNeocortex in the Spotlight: Concepts, Questions, and Methods -- Principles and Fundamentals of Optical Imaging -- Optical Properties of Neural Tissue -- Fluorescent Indicators for Functional Optical Imaging -- Optogenetic Tools for Control of Neural Activity -- In Vivo Dendritic Mapping of Sensory Inputs in Cortical Neurons -- In Vivo Population Imaging of Dendritic Integration in Neocortex -- Voltage-Sensitive Dye Imaging of Cortical Dynamics -- Two-Photon Imaging of Neuronal Network Dynamics in Neocortex -- Chronic Two-Photon Imaging of Neural Activity in the Anesthetized and Awake Behaving Rodent -- Neocortical Circuit Interrogation with Optogenetics -- Imaging of Astrocytic Activity in Living Rodents -- Imaging Morphology and Function of Cortical Microglia -- Functional Imaging of Cerebral Oxygenation with Intrinsic Optical Contrast and Phosphorescent Probes -- Laser Speckle Imaging of Cerebral Blood Flow -- Two-Photon Microscopy to Measure Blood Flow and Concurrent Brain Cell Activity.
520			_aThe application of optical methods for investigating neocortical circuit dynamics has greatly expanded in recent years, providing novel insights into the fascinating world of brain function. Optical Imaging of Neocortical Dynamics presents a guide to these indispensible tools, which cover a broad range of spatiotemporal scales and a  large variety of signaling aspects, ranging from voltage changes to metabolic states. This detailed volume specifically explores methods that are applied in experiments on living brains (in vivo) and that relate to functional properties on the spatial scale of cortical circuits.  Beginning with an introductory section that focuses on physical fundamentals of optical imaging as well as molecular tools used for in vivo optical imaging and optogenetic control, the book continues with the most relevant methods and their applications to investigate changes in neuronal and glial activity states as well as optical imaging methods probing metabolic states.  Written for the Neuromethods series, this volume contains the kind of detail and key implementation advice that ensures successful results in the lab.   Practical and easy to use, Optical Imaging of Neocortical Dynamics serves as an ideal guide for researchers who aim to apply these highly valuable tools to their own neuroscientific studies.
988			_aSpringer_Protocols_2014
650		7	_2embne _9138462 _aSistema nervioso
650		7	_9260434 _aCerebro _xAnatomía
776	0	8	_iPrinted edition: _z9781627037860
776	0	8	_iPrinted edition: _z9781627037846
776	0	8	_iPrinted edition: _z9781493959709
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-62703-785-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b01/2024 _dz _eIG _zSI