000			03717nam a22003975i 4500
999			_c392640 _d392640
001			392640
003			ES-MaUEC
005			20231103141718.0
006			a||||fo|||| 00| 0
007			cr nn 008mamaa
008			100301s2006 xxu| o |||| 0|eng d
020			_a9781592599646
024	7		_a10.1385/1592599648 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRM301.25 _b2006 EB
245	0	0	_aBioinformatics and Drug Discovery _cedited by Richard S. Larson
250			_a1st edition 2006
264		1	_aTotowa, NJ _bHumana Press _c2006
300			_a1 recurso en línea (X, 444 páginas) _b103 ilustraciones
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v316
505	0		_aNew Strategies in Drug Discovery -- Basic Microarray Analysis -- From Microarray to Biological Networks -- Microarray Analysis in Drug Discovery and Clinical Applications -- Ontology-Driven Approaches to Analyzing Data in Functional Genomics -- Gene Evolution and Drug Discovery -- Standardization of Microarray and Pharmacogenomics Data -- Clinical Applications of Bioinformatics, Genomics, and Pharmacogenomics -- Protein Interactions Probed With Mass Spectrometry -- Discovering New Drug-Targeting Sites on Flexible Multidomain Protein Kinases -- Nuclear Magnetic Resonance-Based Screening Methods for Drug Discovery -- Receptor-Binding Sites -- In Silico Protein Design -- Chemical Database Preparation for Compound Acquisition or Virtual Screening -- Bioinformatics Platform Development.
520			_aMany of the new technologies that are transforming drug discovery require a high degree of interdisciplinary expertise in physical science, life science, and computer science for bioinformatic analysis of their output. In Bioinformatics and Drug Discovery, a panel of researchers from academic and pharmaceutical laboratories describes readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the identification of specific drug candidates. The authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situations. Because these technologies are still emergent, each chapter contains an extended introduction that explains the theory and application of the technology and techniques described. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and highly practical, Bioinformatics and Drug Discovery makes it possible to apply in the research laboratory the powerful new technologies that promise to greatly improve and speed up the discovery of new drugs.
988			_aSpringer_Protocols_2006
650		7	_2embne _9137893 _aFarmacología _vManuales de laboratorio
650		7	_2embne _9155839 _aBiotecnología farmacéutica _vManuales de laboratorio
776	0	8	_iPrinted edition: _z9781617375095
776	0	8	_iPrinted edition: _z9781588293466
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/1592599648 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b11/2023 _dz _eu _zSI