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008			160831s2016 xxu| o |||| 0|eng d
020			_a9781493940110
024	7		_a10.1007/978-1-4939-4011-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC643 _b2016 Eb
245	0	0	_aChronic Myeloid Leukemia : _bMethods and Protocols _cedited by Shaoguang Li, Haojian Zhang
250			_a1st edition 2016
264		1	_aNew York, NY _bSpringer International Publishing _c2016
300			_a1 recurso en línea (XI, 257 páginas) _b63 ilustraciones, 43 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1465
505	0		_aMolecular Detection of BCR-ABL in Chronic Myeloid Leukemia -- Induction of Chronic Myeloid Leukemia in Mice -- CML Mouse Model Generated from Leukemia Stem Cells -- Immunological Analyses of Leukemia Stem Cells -- Cell Cycle Analysis of CML Stem Cells using Hoechst33342 and Propidium Iodide -- Histological and In Vivo Microscopic Analysis of the Bone Marrow Microenvironment in a Murine Model of Chronic Myelogenous Leukemia -- The Culture Repopulation Ability (CRA) Assay and Incubation in Low Oxygen to Test Anti-Leukemic Drugs on Imatinib-resistant CML Stem-like Cells -- Tumor Suppressor Analysis in CML -- Detecting Autophagy and Autophagy Flux in Chronic Myeloid Leukemia Cells Using a Cyto ID Fluorescence Spectrophotometric Assay -- DREAM, A Simple Method for DNA Methylation Profiling by High Throughput Sequencing -- ChIP-seq Analysis of Human Chronic Myeloid Leukemia Cells -- Quantitative Proteomics Analysis of Leukemia Cells -- A Convenient Cell Culture Model for CML Acquired Resistance through BCR-ABL Mutations -- High Throughput Screening of Tyrosine Kinase Inhibitor Resistant Genes in CML -- Biological Analysis of Human CML Stem Cells; Xenograft Model of Chronic Phase Human Chronic Myeloid Leukemia -- New Mouse Models to Investigate the Efficacy of Drug Combinations in Human Chronic Myeloid Leukemia -- miRNome Analysis of CML Cells -- An Integrative Analysis of microRNA and mRNA Profiling in CML Stem Cells -- Single Cell Cytokine Profiling to Investigate Cellular Functional Diversity in Hematopoietic Malignancies. .
520			_aThis volume highlights the molecular and cellular methods used in studying Chronic Myeloid Leukimia (CML) pathogenesis and stem cell biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Chronic Myeloid Leukemia: Methods and Protocols aims to ensure successful results in the further study of this vital field.
988			_aSpringer_Protocols_2016
650		7	_2embne _9676045 _aLeucemia mieloide crónica _vManuales de laboratorio
776	0	8	_iPrinted edition: _z9781493940097
776	0	8	_iPrinted edition: _z9781493940103
776	0	8	_iPrinted edition: _z9781493981526
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-4011-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b11/2023 _dz _eu _zSI