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020 _a9781617795978
024 7 _a10.1007/978-1-61779-597-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC321
_b2012 EB
245 0 0 _aZebrafish Protocols for Neurobehavioral Research
_cedited by Allan V. Kalueff, Adam Michael Stewart
250 _a1st edition 2012
264 1 _aTotowa, NJ
_bHumana Press
_c2012
300 _a1 recurso en línea (XVII, 357 páginas)
_b103 ilustraciones, 41 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aNeuromethods
_x1940-6045
_v66
505 0 _aMeasuring Larval Zebrafish Behavior: Locomotion, Thigmotaxis, and Startle -- The Light-Dark Preference Test for Larval Zebrafish -- Assessment of Thigmotaxis in Larval Zebrafish -- Zebrafish and Drug Development: A Behavioral Assay System for Probing Nicotine Function in Larval Zebrafish -- Olfactory Evoked Activity Assay for Larval Zebrafish -- Qualitative and Quantitative Measurements of the Optokinetic Response in Larval Zebrafish -- Automated Imaging of Visual Recognition Memory in Larval Zebrafish -- Automated Conditioning in Larval Zebrafish -- A Method to Quantify Basal and Stress-Induced Cortisol Response in Larval Zebrafish -- A Method for Sorting Zebrafish on the Exploratory-Bold Behavioral Axis -- Nocifensive Behavior in Adult and Larval Zebrafish -- Use of a Split Depth and Visual Cliff Apparatus to Measure the Diving Response in Zebrafish -- Adapting the Open Field Test to Assess Anxiety-Related Behavior in Zebrafish -- Behavioral and Pharmacological Aspects of Anxiety in the Light/Dark Preference Test -- A High Throughput and Inexpensive Assay for Anxiety-Related Behaviors in the Zebrafish, Based on Place Preference and Latency to Feed -- Automated Tracking of Zebrafish Shoals and the Analysis of Shoaling Behavior -- Assessing Social Behavior Phenotypes in Adult Zebrafish: Shoaling, Social Preference, and Mirror Biting Tests -- Measuring Effects of Psychostimulants on Egocentric Spatial Learning and Memory in Adult Zebrafish -- Cued Fear Conditioning in Zebrafish (Danio rerio) -- Assessing Learning and Memory Through the Active Avoidance Paradigm -- Assessing Habituation Phenotypes in Adult Zebrafish: Intra- and Inter-Trial Habituation in the Novel Tank Test -- Assessing Startle Responses and Their Habituation in Adult Zebrafish -- QTL Mapping Using Behavioral Traits in the Adult Zebrafish -- Assessing Epilepsy-Related Behavioral Phenotypes in Adult Zebrafish -- Rapid Method for Acute Intracerebroventricular Injection in Adult Zebrafish -- Western Blotting Assay for Egr-1 Immediate Early Gene in Brain Tissue of Zebrafish Applied to Neuroethological Study -- Utilizing the Zebrafish Neurophenome Project (ZNP) Database for Analyses of Complex Neurophenotypes in Zebrafish Models.
520 _aZebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research.  Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders.  Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.
988 _aSpringer_Protocols_2012
650 7 _2embne
_9158907
_aNeurociencias
776 0 8 _iPrinted edition:
_z9781617795985
776 0 8 _iPrinted edition:
_z9781617795961
776 0 8 _iPrinted edition:
_z9781493960026
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-61779-597-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b10/2023
_dz
_ean
_zSI