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008			131021s2014 xxu| fo |||| 0|eng d
020			_a9781627036733
024	7		_a10.1007/978-1-62703-673-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRM666 .P415 _b2014 EB
245	0	0	_aTherapeutic Peptides : _bMethods and Protocols _cedited by Andrew E. Nixon
250			_a1st edition 2014
264		1	_aTotowa, NJ _bHumana Press _c2014
300			_a1 recurso en línea (XI, 279 páginas) _b53 ilustraciones, 8 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v1088
505	0		_aDesign of Phage-Displayed Cystine-Stabilized Mini-Protein Libraries for Proteinaceous Binder Engineering -- Construction of a Filamentous Phage Display Peptide Library -- Engineering Bio-Active Peptide-Based Therapeutic Molecules -- T7 Lytic Phage-Displayed Peptide Libraries: Construction and Diversity Characterization -- Affinity Selection Using Filamentous Phage Display -- Bioprospecting Open Reading Frames for Peptide Effectors -- Identification of Ideal Peptides for Heterovalent Ligands -- Substrate Phage Display for Protease Substrate Sequence Characterization: Bovine Factor Xa as a Model System -- Engineering Peptide Therapeutics Using MIMETIBODY™ Technology -- Evaluation of Peptides as Protease Inhibitors and Stimulators -- Assessment of Antimicrobial (Host Defense) Peptides as Anti-Cancer Agents -- Peptide Labelling Strategies for Imaging Agents -- Peptide Optimization and Conjugation Strategies in the Development of Molecularly Targeted Magnetic Resonance Imaging Contrast Agents -- Evaluation of Prenylated Peptides for Use in Cellular Imaging and Biochemical Analysis -- Ultraviolet Absorption Spectroscopy of Peptides -- Fluorescence Spectroscopy of Peptides -- Circular Dichroism of Peptides -- Fourier Transform Infrared Spectroscopy of Peptides.
520			_aTherapeutic Peptides: Methods and Protocols features biological methods for the preparation of peptide phage display libraries using both filamentous and lytic phage.  With contributions from renowned authors in the field, the book also explores selection and screening of the prepared peptide libraries for peptides with the desired function and the subsequent characterization of the identified peptides.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Practical and dependable,  Therapeutic Peptides: Methods and Protocols is an ideal guide for researchers from all backgrounds seeking methods for the identification of therapeutic peptide candidates.
988			_aSpringer_Protocols_2014
650		7	_2embne _9146243 _aPéptidos _xUso terapéutico
776	0	8	_iPrinted edition: _z9781627036726
776	0	8	_iPrinted edition: _z9781627036740
776	0	8	_iPrinted edition: _z9781493957125
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-62703-673-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b10/2023 _dz _ean _zSI