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008			120104s2012 xxu| fo |||| 0|eng d
020			_a9781617794483
024	7		_a10.1007/978-1-61779-448-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH450 _b2012 EB
245	0	0	_aExpression Profiling in Neuroscience _cedited by Yannis Karamanos
250			_a1st edition 2012
264		1	_aTotowa, NJ _bHumana Press _c2012
300			_a1 recurso en línea (XIII, 284 páginas) _b55 ilustraciones, 33 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNeuromethods _x1940-6045 _v64
505	0		_aDNA Microarrays for Gene Expression Analysis in Brain Tissue and Cell Lines -- Gene Expression Profiling Using the Terminal Continuation (TC) RNA Amplification Method for Small Input Samples in Neuroscience -- Expression Profiling In Brain Disorders -- Endothelial Cell Heterogeneity of Blood-Brain Barrier Gene Expression: Analysis by LCM/qRT-PCR -- Gene Expression Profiling Using 3' Digital Tag Approach -- Sharing Expression Profiling Data with Gemma -- Two-Dimensional Protein Analysis of Neural Stem Cells -- iTRAQ Proteomics Profiling of Regulatory Proteins During Oligodendrocyte Differentiation -- Protein Profiling of the Brain: Proteomics of Isolated Tissues and Cells -- The Proteome of Brain Capillary Endothelial Cells: Towards a Molecular Characterization of an In Vitro Blood-Brain Barrier Model -- MALDI Imaging Technology Application in Neurosciences: From History to Perspectives -- Profiling of HIV Proteins in Cerebrospinal Fluid -- Proteomic Profiling of Cerebrospinal Fluid -- New Nanotechnology Applications in Single Cell Analysis: Why and How.
520			_aTranscriptomics and proteomics, studying the profile of the expression of nucleic acids and proteins respectively, are increasingly applied to gain a mechanistic insight into a wide spectrum of investigation, and the use of expression profiling studies for the central nervous system and brain function aids in the understanding of neurodegenerative disorders and tumor development mechanisms.  In Expression Profiling in Neuroscience, expert researchers provide a survey of the most commonly used approaches in the field and scan the different ways of studying the central nervous system/brain environment through expression profiling.  The first part addresses the gene expression profiling of the brain at a large scale or to a specific cell type such as blood-brain barrier endothelium. Then, the second part describes the protein expression studies and the different technologies applied.  Written for the popular Neuromethods series, chapters include corresponding background information, tested laboratory protocols, and step-by-step methods for reproducible laboratory experiments.   Detailed and authoritative, Expression Profiling in Neuroscience presents the state-of-the-art techniques necessary to expand research further into this vital area of study.
988			_aSpringer_Protocols_2012
650		7	_2embne _9162770 _aExpresión génica _vManuales de laboratorio
776	0	8	_iPrinted edition: _z9781617794476
776	0	8	_iPrinted edition: _z9781617794490
776	0	8	_iPrinted edition: _z9781493962235
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-61779-448-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE