000			03996nam a22004095i 4500
999			_c392529 _d392529
001			392529
003			ES-MaUEC
005			20231118195618.0
006			a||||fo|||| 00| 0
007			cr nn 008mamaa
008			160708s2016 xxu| fo |||| 0|eng d
020			_a9781493934720
024	7		_a10.1007/978-1-4939-3472-0 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP551 _b2016 EB
245	0	0	_aAnalysis of Post-Translational Modifications and Proteolysis in Neuroscience _cedited by Jennifer Elizabeth Grant, Hong Li
250			_a1st edition 2016
264		1	_aNew York, NY _bSpringer International Publishing _c2016
300			_a1 recurso en línea (XV, 290 páginas) _b49 ilustraciones, 29 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aNeuromethods _x1940-6045 _v114
505	0		_aProteomic Analysis of Post-Translational Modifications in Neurobiology -- A Boronic Acid-based Enrichment for Site-specific Identification of the N-glycoproteome using MS-based Proteomics -- Site-specific Localization of D-Amino Acids in Bioactive Peptides by Ion Mobility Spectrometry -- Quantitative Profiling of Reversible Cysteome Modification under Nitrosative Stress -- Label-free LC-MS/MS Comparative Analysis of Protein S-nitrosome in Synaptosomes from Wild Type and APP Transgenic Mice -- Proteomics Identification of Redox-Sensitive Nuclear Protein Targets Of Human Thioredoxin 1 from SHSY-5Y Neuroblastoma Cell Line -- Identification and Quantification of K63-Ubiquitinated Proteins in Neuronal Cells by High-Resolution Mass Spectrometry -- Phosphorylation Site Profiling of NG108 Cells Using Quadrupole/Orbitrap Mass Spectrometry -- Phosphoproteomics of Tyrosine Kinases in the Nervous System -- Analysis of PINK1 and CaMKII Substrates Using Mass Spectrometry-Based Proteomics -- Liquid Chromatography-Tandem Mass Spectrometry Analysis of Tau Phosphorylation -- Identification of Protease Substrates in Complex Proteomes by iTRAQ-TAILS -- Proteolytic Processing of Neuropeptides -- Isotope Dilution Analysis of Myelin Basic Protein Degradation after Brain Injury -- Identification and Characterization of Protein Post-Translational Modifications byDifferential Fluorescent Labeling -- Mass Spectrometric Detection of Detyrosination and Polyglutamyation on the C-Terminal Region of Brain Tubulin -- Determination of polyhydroxybutyrate (PHB) Post-Translational Modifications of Proteins Using Mass Spectrometry. .
520			_aThis volume highlights proteomics studies of quantitative PTM changes in both peripheral and central nervous system proteomes utilizing the most recent advances in mass spectrometry. Chapters include practical information pertaining to the fundamentals of sample preparation, liquid chromatography, and tandem mass spectrometry instrumental analysis and will elucidate best practices in the interpretation of data using modern bioinformatics approaches. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Analysis of Post-Translational Modifications and Proteolysis in Neuroscience aims to ensure successful results in the further study of this vital field.
988			_aSpringer_Protocols_2016
650		7	_2embne _9141447 _aEspectrometría de masas
650		7	_2embne _9158907 _aNeurociencias
776	0	8	_iPrinted edition: _z9781493934706
776	0	8	_iPrinted edition: _z9781493934713
776	0	8	_iPrinted edition: _z9781493980581
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-3472-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b11/2023 _dz _ean _zSI