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007			cr nn 008mamaa
008			100715s2010 xxu| o |||| 0|eng d
020			_a9781607615859
024	7		_a10.1007/978-1-60761-585-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQR189 _b2010 EB
245	0	0	_aVaccine Adjuvants : _bMethods and Protocols _cedited by Gwyn Davies
250			_a1st edition 2010
264		1	_aTotowa, NJ _bHumana Press _c2010
300			_a1 recurso en línea (X, 314 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v626
505	0		_aImmunology of Vaccine Adjuvants -- Preclinical Development of AS04 -- Nonclinical Safety Assessment of Vaccines and Adjuvants -- Aluminum Adjuvants: Preparation, Application, Dosage, and Formulation with Antigen -- Freund's Complete and Incomplete Adjuvants, Preparation, and Quality Control Standards for Experimental Laboratory Animals Use -- Liposomal Adjuvants: Preparation and Formulation with Antigens -- Micro/Nanoparticle Adjuvants: Preparation and Formulation with Antigens -- Adjuvant Activity on Human Cells In Vitro -- Adjuvant Activity on Murine and Human Macrophages -- In Vitro Effects of Adjuvants on B Cells -- NKT Cell Responses to Glycolipid Activation -- Tracking Dendritic Cells In Vivo -- Adjuvant Effects on Antibody Titre -- Functional Antibody Assays -- Determining Adjuvant Activity on T-Cell Function In Vivo: Th Cells -- Quantitative Multiparameter Assays to Measure the Effect of Adjuvants on Human Antigen-Specific CD8 T-Cell Responses -- Large-Animal Model for Establishing E/T Ratio of Adjuvants -- Determining the Activity of Mucosal Adjuvants -- Adjuvant Activity of Cytokines.
520			_aSpanning from discoveries in fundamental immunology to industrial and commercial concerns, the study of vaccine adjuvants has developed into an exciting area of work with great, vital potential in innovating techniques in which adjuvants may steer the immune system towards the responses required by unmet vaccination needs. In Vaccine Adjuvants: Methods and Protocols, expert researchers in the field provide clear and concise guidance on how to go about assessing the activity of adjuvant products. Rather than describing individual adjuvants, the volume strives to include detailed, practical information on measuring the responses produced by adjuvants in order to be relevant to the widest array of experiments. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and versatile, Vaccine Adjuvants: Methods and Protocols will enable those already pursuing vaccine adjuvant research, while also serving to stimulate discussion on how to best standardize adjuvant testing in order to facilitate meaningful comparisons, and above all, to aid in the prediction of which new products will most effectively and safely help to solve the current challenges in vaccination.
988			_aSpringer_Protocols_2010
650		7	_2embne _9140409 _aVacunas
650		7	_2embne _9138330 _aInmunología
776	0	8	_iPrinted edition: _z9781607615866
776	0	8	_iPrinted edition: _z9781607615842
776	0	8	_iPrinted edition: _z9781493957118
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60761-585-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2023 _dz _eIG _zSI