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008			120604s2012 xxu| o |||| 0|eng d
020			_a9781617798702
024	7		_a10.1007/978-1-61779-870-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH447 _b2012 EB
245	0	0	_aData Production and Analysis in Population Genomics : _bMethods and Protocols _cedited by François Pompanon, Aurélie Bonin
250			_a1st edition 2012
264		1	_aTotowa, NJ _bHumana Press _c2012
300			_a1 recurso en línea (XI, 337 páginas) _b67 ilustraciones, 16 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v888
505	0		_aSampling in Landscape Genomics -- oligoTag: A Program for Designing Sets of Tags for Next-Generation Sequencing of Multiplexed Samples -- SNP Discovery in Non-Model Organisms Using 454 Next Generation Sequencing -- ISIF (In Silico Fingerprinting): A User-Friendly in silico AFLP Program -- Diversity Arrays Technology (DArT) - A Generic Genome Profiling Technology on Open Platforms -- Two Methods to Easily Obtain Nucleotide Sequences from AFLP Loci of Interest -- Roche Genome Sequencer FLX Based High-Throughput Sequencing of Ancient DNA -- Preparation of Normalized cDNA Libraries for 454 Titanium Transcriptome Sequencing -- RAD Paired-End Sequencing for Local de novo Assembly and SNP Discovery in Non-Model Organisms -- Automated Scoring of AFLPs Using RawGeno v 2.0, A Free R CRAN Library -- Haplotype Inference -- Allele Identification in Assembled Genomic Sequence Datasets -- Multiple-Testing in Large-Scale Genetic Studies -- Population Genomic Analysis of Model and Non-Model Species Using Sequenced RAD Tags -- Analysis and Management of Gene and Allelic Diversity in Subdivided Populations Using the Software Program METAPOP -- DETSEL: An R-Package to Detect Marker Loci Responding to Selection -- Use of Qualitative Environmental and Phenotypic Variables in the Context of Allele Distribution Models: Detecting Signatures of Selection in the Genome of Lake Victoria Cichilds -- Genomic Scan as a Tool for Assessing the Genetic Component of Phenotypic Variance in Wild Populations.
520			_aPopulation genomics is a recently emerged discipline, which aims at understanding how evolutionary processes influence genetic variation across genomes. Today, in the era of cheaper next-generation sequencing, it is no longer as daunting to obtain whole genome data for any species of interest and population genomics is now conceivable in a wide range of fields, from medicine and pharmacology to ecology and evolutionary biology. However, because of the lack of reference genome and of enough a priori data on the polymorphism, population genomics analyses will still involve higher constraints for researchers working on non-model organisms, as regards the choice of the genotyping/sequencing technique or that of the analysis methods. Therefore, Data Production and Analysis in Population Genomics purposely puts emphasis on protocols and methods that are applicable to species where genomic resources are still scarce. It is divided into three convenient sections, each one tackling one of the main challenges facing scientists setting up a population genomics study. The first section helps devising a sampling and/or experimental design suitable to address the biological question of interest. The second section addresses how to implement the best genotyping or sequencing method to obtain the required data given the time and cost constraints as well as the other genetic resources already available. Finally, the last section is about making the most of the (generally huge) dataset produced by using appropriate analysis methods in order to reach a biologically relevant conclusion. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, advice on methodology and implementation, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and easily accessible, Data Production and Analysis in Population Genomics serves a wide readership by providing guidelines to help choose and implement the best experimental or analytical strategy for a given purpose.
988			_aSpringer_Protocols_2012
650		7	_2embne _9162605 _aGenomas
776	0	8	_iPrinted edition: _z9781617798696
776	0	8	_iPrinted edition: _z9781617798719
776	0	8	_iPrinted edition: _z9781493959136
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-61779-870-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2023 _dz _eIG _zSI