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020 _a9781493923779
024 7 _a10.1007/978-1-4939-2377-9
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQH506
_b2015 EB
245 0 0 _aMetabonomics :
_bMethods and Protocols
_cedited by Jacob T. Bjerrum
250 _a1st edition 2015
264 1 _aNew York, NY
_bSpringer International Publishing
_c2015
300 _a1 recurso en línea (X, 259 páginas)
_b74 ilustraciones, 48 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1277
505 0 _aMetabonomics - Analytical Techniques and Associated Chemometrics at a Glance -- Sample Collection and Preparation of Biofluids and Extracts for NMR Spectroscopy -- NMR Spectroscopy of Biofluids and Extracts -- High-resolution Magic-Angle-Spinning NMR Spectroscopy of Intact Tissue -- Sample Collection and Preparation of Biofluids and Extracts For Liquid Chromatography-Mass Spectrometry -- Liquid Chromatography-Mass Spectrometry of Biofluids and Extracts -- Sample Collection and Preparation of Biofluids and Extracts For Gas-Chromatography-Mass Spectrometry -- Gas Chromatography-Mass Spectrometry of Biofluids and Extracts -- Capillary Electrophoresis Mass Spectrometry -- Preprocessing of Raw Metabonomics Data -- Extracting Meaningful Information From Metabonomics Data Using Multivariate Statistics -- Combining Metabonomics and Other -omics Data -- The Strengths and Weaknesses of NMR Spectroscopy and Mass Spectrometry With Particular Focus on Metabolomics Research -- Metabonomics and Drug Development -- Metabonomics and Toxicology -- Metabonomics and Diagnostics -- Metabonomics and Systems Biology.
520 _aThis volume on metabonomics provides detailed information on the procedures involved in nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GS-MS), liquid chromatography-mass spectrometry (LC-MS), and capillary electrophoresis-mass spectrometry (CE-MS). Chapters focus on technologies and chemometrics,  generation of metabonomics data, extraction of meaningful information from data,  drug development, toxicology, diagnostics,  and describing metabonomics as an essential part of systems biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
988 _aSpringer_Protocols_2015
650 7 _2embne
_9139103
_aBiología molecular
650 7 _2embne
_9138638
_aMetabolismo
776 0 8 _iPrinted edition:
_z9781493923786
776 0 8 _iPrinted edition:
_z9781493923762
776 0 8 _iPrinted edition:
_z9781493948376
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-2377-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b09/2023
_dz
_eIG
_zSI