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008			100301s1996 xxu| o |||| 0|eng d
020			_a9781592595884
024	7		_a10.1385/0896033341 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQR189 _b1996 EB
245	0	0	_aVaccine Protocols _cedited by Andrew P. Robinson, Graham H. Farrar, Christopher N. Wiblin
250			_a1st edition 1996
264		1	_aTotowa, NJ _bHumana Press _c1996
300			_a1 recurso en línea (X, 317 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Medicine _x1940-6037 _v4
505	0		_aOverview of Vaccines -- Temperature-Sensitive Mutant Vaccines -- Live Viral Vectors -- Development of Attenuated Salmonella Strains that Express Heterologous Antigens -- Chimeric Proteins -- Synthetic Peptides -- Genetic Detoxification of Bacterial Toxins -- Polysaccharicb-Conjugate Vaccines -- The Use of Adjuvants in Experimental Vaccines -- The Use of Adjuvants in Experimental Vaccines -- The Use of Adjuvants in Experimental Vaccines -- The Use of Adjuvants in Experimental Vaccines -- Microencapsulation of Vaccines -- Lyophilization of Vaccines -- Stimulation of Mucosal Immunity -- Induction and Detection of T-Cell Responses -- Immunological Characterization -- Severe Combined lmmunodeficient (SCID) Mice in Vaccine Assessment -- Clinical Trials -- Assuring the Quality of Vaccines -- DNA Vaccines -- Cancer Vaccines.
520			_aThe production of a book devoted to Vaccine Protocols has proved to be a complex task; the variety of procedures required to design, develop, pro­ duce, and assess a vaccine is immense and covers aspects of chemistry, bio­ chemistry, molecular biology, and immunology. Many of the previous volumes in the Methods in Molecular Biology series provide the background required for work on vaccines; of particular interest are the volumes on Immunochemi­ cal Protocols, Practical Molecular Virology, Proteins, and Nucleic Acids. In the volume on Vaccine Protocols, we have tried to cover the latest scientific methods for the design, production, and assessment of vaccines against viruses, bacteria, and parasites. Essentially, the volume is comprised of three basic chapter types. First, a number of chapters describe in detail the development and production of vac­ cines by specific techniques, including genetic manipulation of viruses or bac­ teria to produce live attenuated vaccines or inactivated toxins, and the production of synthetic peptides and conjugate vaccines. Second, a similar number of chapters describe more general techniques that can be used for the formulation, delivery, and assessment of immune responses to vaccines.
988			_aSpringer_Protocols_1996
650		7	_2embne _9140409 _aVacunas
776	0	8	_iPrinted edition: _z9781489944092
776	0	8	_iPrinted edition: _z9781489944085
776	0	8	_iPrinted edition: _z9780896033344
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/0896033341 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2023 _dz _eIG _zSI