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008			110930s2012 xxu| o |||| 0|eng d
020			_a9781617793493
024	7		_a10.1007/978-1-61779-349-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQH431 _b2012 EB
245	0	0	_aChemical Genomics and Proteomics : _bReviews and Protocols _cedited by Edward D. Zanders
250			_a1st edition 2012
264		1	_aTotowa, NJ _bHumana Press _c2012
300			_a1 recurso en línea (XI, 243 páginas) _b71 ilustraciones
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v800
505	0		_aOverview of Chemical Genomics and Proteomics -- Exploring Chemical Space: Recent Advances in Chemistry -- In Silico Design of Small Molecules -- Surface Plasmon Resonance for Proteomics -- Biomimetic Affinity Ligands for Immunoglobulins Based on the Multicomponent Ugi Reaction -- Preparation of Photo-Cross-Linked Small Molecule Affinity Matrices for Affinity Selection of Protein Targets for Biologically Active Small Molecules -- Profiling Cellular Myristoylation and Palmitoylation Using ω-Alkynyl Fatty Acids -- Fluorescence Labels in Kinases (FLiK): A High-Throughput Kinase Binding Assay for the Identification of DFG-Out Binding Ligands -- Electrochemical Aptamer Sensor for Small Molecule Assays -- Miniaturized, Microarray-Based Assays for Chemical Proteomic Studies of Protein Function -- Glycan Microarrays -- Resolving Bottlenecks for Recombinant Protein Expression in E. coli -- Recombinant Protein Expression in the Baculovirus-Infected Insect Cell System -- Systems for the Cell-Free Synthesis of Proteins -- Protein Identification by MALDI-TOF Mass Spectrometry.
520			_aChemical genomics technology has been steadily improving, delivering new biological probes and drugs, and the explicit use of the term 'chemical proteomics' has increased with it, as proteins have always been at the heart of this technology.  In Chemical Genomics and Proteomics: Reviews and Protocols, experts in the field present updated reviews of the chemistry of small molecules and their interaction with protein targets as well as detailed protocols that cover different types of ligands, carbohydrates, and lipids.  For example, the generation of their protein targets and methods for measuring their interactions is covered.  Written in the highly successful Methods in Molecular Biology™ series format, methodology chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.   Thorough and up to date,  Chemical Genomics and Proteomics: Reviews and Protocols aims to provide inspiration to those who wish to use chemical genomics and proteomics in their work and develop this young field into full maturity through the incorporation of the new biological and chemical technologies beginning to emerge here.
988			_aSpringer_Protocols_2012
650		7	_2embne _9430647 _aProteómica
650		7	_2embne _9165192 _aFarmacogenómica
776	0	8	_iPrinted edition: _z9781617793486
776	0	8	_iPrinted edition: _z9781617793509
776	0	8	_iPrinted edition: _z9781493962266
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-61779-349-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2023 _dz _eIG _zSI