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008			110727s2011 xxu| o |||| 0|eng d
020			_a9781617792434
024	7		_a10.1007/978-1-61779-243-4 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP572 .S4 _b2011 EB
245	0	0	_aAndrogen Action : _bMethods and Protocols _cedited by Fahri Saatcioglu
250			_a1st edition 2011
264		1	_aTotowa, NJ _bHumana Press _c2011
300			_a1 recurso en línea (XI, 386 páginas) _b68 ilustraciones, 12 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v776
505	0		_aMolecular Mechanisms of Androgen Action - A Historical Perspective -- Androgen Action during Prostate Carcinogenesis -- Androgen Quantitation in Prostate Cancer Tissue using Liquid Chromatography Tandem Mass Spectrometry -- Ligand Competition Binding Assay for the Androgen Receptor -- Analysis of Androgen Receptor Activity by Reporter Gene Assays -- Identification and Characterization of Androgen Response Elements -- In vitro and In vivo Silencing of the Androgen Receptor -- Analysis of Interdomain Interactions of the Androgen Receptor -- Methods to Study Dynamic Interaction of Androgen Receptor with Chromatin in Living Cells -- FRET Analysis of Androgen Receptor Structure and Biochemistry in Living Cells -- Analysis of Nuclear Receptor Acetylation -- Analysis of Androgen Receptor SUMOylation -- Analysis of Ligand-specific Co-repressor Binding to the Androgen Receptor -- Detection of Ligand-selective Interactions of the Human Androgen Receptor by SELDI-MS-TOF -- Global Identification of Androgen Response Elements -- Tissue Specific Knockout of Androgen Receptor in Mice -- Methodology to Investigate Androgen-sensitive and Castration-resistant Human Prostate Cancer Xenografts in Preclinical Setting -- Automated Microscopy and Image Analysis for Androgen Receptor Function -- Androgen Regulation of ETS-gene Fusion Transcripts in Prostate Cancer -- Regulation of Apoptosis by Androgens in Prostate Cancer Cells -- Analysis of Androgen Receptor Rapid Actions in Cellular Signaling Pathways: Receptor /Src Association -- Analysis of Androgen-induced Increase in Lipid Accumulation in Prostate Cancer Cells.
520			_aAndrogens play a critical role in the development and maintenance of the male reproductive system and affect important physiological processes and pathological conditions, including the homeostasis of the normal prostate and prostate cancer. Androgen Action: Methods and Protocols is designed to provide a tool box to study various phases of androgen action, from its entry to the cell to the phenotypic response that the cell mounts, with up-to-date techniques for biochemists, molecular biologists, cell biologists, geneticists, and pathologists. The volume opens with a brief review of the research history on androgen action and prostate carcinogenesis, followed by chapters that cover state-of-the-art methods to determine androgen levels in biological tissues and fluids, experimental procedures to study the various aspects of androgen receptor activity, and methodology to study salient examples of interactions between androgen signalling and other major signalling pathways in cells. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and easily accessible, Androgen Action: Methods and Protocols provides a comprehensive overview of, and practical guidance on, the diverse methodologies that are propelling androgen action research forward, both for normal physiology as well as in disease states.
988			_aSpringer_Protocols_2011
650		7	_2embne _9675054 _aHormonas sexuales _xEfectos fisiológicos
776	0	8	_iPrinted edition: _z9781617792427
776	0	8	_iPrinted edition: _z9781617792441
776	0	8	_iPrinted edition: _z9781493962013
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-61779-243-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
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998			_b09/2023 _dz _eIG _zSI