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008			110826s2011 xxu| fo |||| 0|eng d
020			_a9781617792199
024	7		_a10.1007/978-1-61779-219-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC78.7 .N83 _b2011 EB
245	0	0	_aIn vivo NMR Imaging : _bMethods and Protocols _cedited by Leif Schröder, Cornelius Faber
250			_a1st edition 2011
264		1	_aTotowa, NJ _bHumana Press _c2011
300			_a1 recurso en línea (IX, 753 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v771
505	0		_aPhysical Basics of NMR -- Spatial Encoding - Basic Imaging Sequences -- Basic Contrast Mechanisms -- Scanner Components -- Small Animal Preparation and Handling in MRI -- Cerebral Perfusion MRI in Mice -- High Field Diffusion Tensor Imaging in Small Animals and Excised Tissue -- The BOLD Effect -- Screening of CEST MR Contrast Agents -- Hyperpolarized Noble Gases as Contrast Agents -- Hyperpolarized Molecules in Solution -- MR Oximetry -- MRI using Intermolecular Multiple-Quantum Coherences -- Experimental Stroke Research: The Contributions of In vivo MRI -- Volumetry and Other Quantitative Measurements to Assess the Rodent Brain -- Models of Neurodegenerative Disease - Alzheimer's Anatomical and Amyloid Plaque Imaging -- MRI in Animal Models of Psychiatric Disorders -- Spectroscopic Imaging of the Mouse Brain -- Spinal Cord - MR of Rodent Models -- Assessment of Cardiac Function -- Plaque Imaging in Murine Models of Cardiovascular Disease -- Interventional MRI in the Cardiovascular System -- MR for the Investigation of Murine Vasculature -- MRI of the Lung: Non-invasive Protocols and Applications to Small Animal Models of Lung Disease -- Characterization of Tumor Vasculature in Mouse Brain by USPIO Contrast-enhanced MRI -- Cancer Models - A Multiparametric Application of MRI in Rodent Hepatic Tumor Model -- BOLD MRI Applied to a Murine Model of Peripheral Artery Disease -- Manganese-enhanced Magnetic Resonance Imaging -- Spin Echo BOLD fMRI on Songbirds -- MRI to Study Embryonic Development -- Mouse Phenotyping with MRI -- Analysis of Freshly Fixed and Museum Invertebrate Specimens using High-resolution, High-throughput MRI -- Applications of Hyperpolarized Agents in Solutions -- Target-specific Paramagnetic and Superparamagnetic Micelles for Molecular MR Imaging -- Tracking Transplanted Cells by MRI - Methods and Protocols -- MRI of CEST Based Reporter Gene.
520			_aNuclear magnetic resonance imaging represents a technique that is indispensable in every day biomedical diagnostics. Thanks to the numerous ways to manipulate and detect an NMR signal, it is possible to obtain a variety of information with excellent spatial and temporal resolution. Today's MRI techniques go far beyond the illustration of pure anatomical structures and include the revealing of processes down to the molecular level. The number of small animal imaging centers relying on MRI as a key method for preclinical research to understand diseases and to test for novel treatments is growing rapidly. In Vivo NMR Imaging: Methods and Protocols is written as an experimental laboratory text to provide a descriptive approach of the various applications of magnetic resonance imaging and its underlying principles. Starting from a compact introduction of basic NMR physics and image encoding techniques suitable for a broad audience in the life sciences, the concept focuses on addressing the many ways of generating contrast in MR images. The authors cover an interdisciplinary range of problems to be addressed by this non-invasive modality, including study protocols for addressing morphological, physiological, functional, and biochemical aspects of various tissues in living organisms. Information about practical aspects of designing experimental studies that follow the special conditions for micro imaging setups are also provided.   Written in the successful Methods in Molecular Biology™ series format, In Vivo NMR Imaging: Methods and Protocols aims to be an experimental compendium of modern in vivo MR imaging with special focus on recent developments in molecular imaging and new protocols for imaging metabolism and molecular markers.
988			_aSpringer_Protocols_2011
650		7	_2embne _9141826 _aResonancia magnética nuclear (Medicina) _vManuales de laboratorio
776	0	8	_iPrinted edition: _z9781617792182
776	0	8	_iPrinted edition: _z9781617792205
776	0	8	_iPrinted edition: _z9781493961726
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-61779-219-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b09/2023 _dz _eu _zSI