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020 _a9781493974566
024 7 _a10.1007/978-1-4939-7456-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQH324.2
_b2018 EB
245 0 0 _aSystems Biology
_cedited by Mariano Bizzarri
250 _a1st edition 2018
264 1 _aNew York, NY
_bSpringer International Publishing
_c2018
300 _a1 recurso en línea (XVII, 364 páginas)
_b102 ilustraciones, 83 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1702
505 0 _aConceptual Challenges in the Theoretical Foundations of Systems Biology -- An Integrative Approach toward Biology, Organisms, and Cancer -- Conceptual Challenges of the Systemic Approach in Understanding Cell Differentiation -- A Primer on Mathematical Modeling in the Study of Organisms and their Parts -- The Search for System's Parameters -- Inverse Problems in Systems Biology: A Critical Review -- Systems Biology Approach and Mathematical Modeling for Analyzing Phase-space Switch during Epithelial-mesenchymal Transition -- Parameters Estimation in Phase-space Landscape Reconstruction of Cell Fate; A Systems Biology Approach -- Complexity of Biochemical and Genetic Responses Reduced using Simple Theoretical Models -- Systems Biology Modelling of Non-linear Cancer Dynamics -- Endogenous Molecular-cellular Network Cancer Theory: A Systems Biology Approach -- A Network-based Integrative Workflow to Unravel Mechanisms Underlying Disease Progression -- Spatiotemporal Fluctuation Analysis of Molecular Diffusion Laws in Live-cell Membranes -- A Method for Cross-species Visualization and Analysis of RNA-sequence Data -- Multi Agent Simulations of Population Behavior (A Promising Tool for Systems Biology) -- Metabolomics: Challenges and Opportunities in Systems Biology Studies -- Systems Biology-driven Hypotheses Tested In Vivo: The Need to Advancing Molecular Imaging Tools. .
520 _aThis volume focuses on methodological aspects of systems biology in order to provide a new theoretical approach with a robust and tailored experimental support. Chapters detail mathematical modeling, methodological issues, modulation of the collective behavior, metabolic, dynamic profiling, and quantitative morphological studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Systems Biology aims to ensure successful results in the further study of this vital field.
988 _aSpringer_Protocols_2018
650 7 _2embne
_9160489
_aBioinformática
776 0 8 _iPrinted edition:
_z9781493974559
776 0 8 _iPrinted edition:
_z9781493974573
776 0 8 _iPrinted edition:
_z9781493984916
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7456-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b10/2023
_dz
_eb
_zSI