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008			100301s2007 xxu| o |||| 0|eng d
020			_a9781597453615
024	7		_a10.1007/978-1-59745-361-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aQP86 _b2007 EB
245	0	0	_aBiological Aging : _bMethods and Protocols _cedited by Trygve O. Tollefsbol
250			_a1st edition 2007
264		1	_aTotowa, NJ _bHumana Press _c2007
300			_a1 recurso en línea (XV, 414 páginas)
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v371
505	0		_aTechniques for Analysis of Biological Aging -- Aging Cell Culture -- Methods to Detect Biomarkers of Cellular Senescence -- Methods for Cell Sorting of Young and Senescent Cells -- Telomere Length Analysis -- A Method to Detect DNA Methyltransferase I Gene Transcription In Vitro in Aging Systems -- A Method to Study the Expression of DNA Methyltransferases in Aging Systems In Vitro -- The Chronological Life Span of Saccharomyces cerevisiae -- Caloric Restriction and Life Span Determination of Yeast Cells -- Methods for Nutrigenomics and Longevity Studies in Drosophila -- Caloric Restriction Mimetics -- Extension of Cell Life Span Using Exogenous Telomerase -- Inducing Cellular Senescence Using Defined Genetic Elements -- Methods of Cellular Senescence Induction Using Oxidative Stress -- Nuclear Transfer Methods to Study Aging -- Use of Ribozymes in Cellular Aging Research -- Methods of Evaluating the Effect of Pharmacological Drugs On Aging and Life Span in Mice -- Identifying Genes that Extend Life Span Using a High-Throughput Screening System -- Application of DNA Microarray Technology to Gerontological Studies -- Detection and Analysis of Somatic Mutations at a lacZ Reporter Locus in Higher Organisms -- Subtractive Hybridization Techniques to Study Cellular Senescence -- Mapping Genetic Polymorphisms Affecting Natural Variation in Drosophila Longevity -- Quantitative Trait Locus (QTL) Mapping in Aging Systems -- 2D Gel Proteomics -- Metabolomics in the Study of Aging and Caloric Restriction.
520			_aBiological Aging: Methods and Protocols investigates the various processes that are affected by the age of an organism. Several new tools for the analysis of biological aging have been introduced recently, and this volume provides methods and protocols for these new techniques in addition to its coverage of established procedures. The editors have carefully selected only those topics that are considered mainstays of the field or are showing promise in revolutionizing this relatively new science. The three main areas of focus in this cutting-edge compendium of biological aging research are: methods that are basic to understanding the fundamental mechanisms of cellular aging; techniques used to intervene in the aging process; and approaches to analyzing the many molecular processes of biological aging. Researchers seeking new technology and techniques will find this volume of tremendous benefit as they move towards new directions in the exciting and expanding field of biological aging.
988			_aSpringer_Protocols_2007
650		7	_2embne _9141231 _aEnvejecimiento _vManuales de laboratorio
650		7	_2embne _9144609 _aLongevidad _vManuales de laboratorio
776	0	8	_iPrinted edition: _z9781588296580
776	0	8	_iPrinted edition: _z9781627039062
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-59745-361-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b10/2023 _dz _eb _zSI