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020 _a9781592595112
024 7 _a10.1385/0896032469
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP620
_b1995 EB
100 1 _aGriffin, Annette M.
_eautor
_9689042
245 1 0 _aComputer Analysis of Sequence Data
_nPart I
_cby Annette M. Griffin, Hugh G. Griffin
250 _a1st edition 1994
264 1 _aTotowa, NJ
_bHumana Press
_c1994
300 _a1 recurso en línea (XII, 372 páginas)
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v24
505 0 _aComputer Analysis of Sequence Data -- GCG: Fragment Assembly Programs -- GCG: Drawing Linear Restriction Maps -- GCG: Drawing Circular Restriction Maps -- GCG: Displaying Restriction Sites and Possible Translations in a DNA Sequence -- GCG: Assembly of Sequences into New Sequence Constructs -- GCG: Comparison of Sequences -- GCG: Production of Multiple Sequence Alignment -- GCG: Database Searching -- GCG: Pattern Recognition -- GCG: Translation of DNA Sequence -- GCG: Analysis of Protein Sequences -- GCG: The Analysis of RNA Secondary Structure -- GCG: Preparing Sequence Data for Publication -- MicroGenie: Introduction and Restriction Enzyme Analysis -- MIicroGenie: Shotgun DNA Sequencing -- MicroGenie: Translation -- MicroGenie: Protein Analysis -- MicroGenie: Homology Searches -- PC/GENE: Sequence Entry and Assembly -- PC/GENE: Restriction Enzyme Analysis -- PC/GENE: Translation and Searches for Protein Coding Regions -- PC/GENE: Sequence Comparisons and Homologies -- PC/GENE: Database Searches -- PC/GENE: Searches for Functional Sites in Nucleic Acids and Proteins -- Using the FASTA Program to Search Protein and DNA Sequence Databases -- Converting Between Sequence Formats -- Obtaining Software via INTERNET -- Submission of Nucleotide Sequence Data to EMBL/GenBank/DDBJ.
520 _aDNA sequencing has become increasingly efficient over the years, resulting in an enormous increase in the amount of data gen- ated. In recent years, the focus of sequencing has shifted, from being the endpoint of a project, to being a starting point. This is especially true for such major initiatives as the human genome project, where vast tracts of DNA of unknown function are sequenced. This sheer volume of available data makes advanced computer methods ess- tial to analysis, and a familiarity with computers and sequence ana- sis software a vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers, a familiarity with sequence analysis software can be important. For instance, gene sequences already present in the databases can be extremely useful in the design of cloning and genetic manipulation experiments. This two-part work on Analysis of Data is designed to be a practical aid to the researcher who uses computers for the acquisition, storage, or analysis of nucleic acid (and/or p- tein) sequences. Each chapter is written such that a competent sci- tist with basic computer literacy can carry out the procedure successfully at the first attempt by simply following the detailed pr- tical instructions that have been described by the author. A Notes section, which is included at the end of each chapter, provides advice on overcoming the common problems and pitfalls sometimes enco- tered by users of the sequence analysis software. Software packages for both the mainframe and personal computers are described.
988 _aSpringer_Protocols_1994
650 7 _2embne
_9140525
_aÁcidos nucleicos
700 1 _aGriffin, Hugh G.
_eautor
_9689043
776 0 8 _iPrinted edition:
_z9780896032460
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1385/0896032469
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b10/2023
_dz
_eb
_zSI