000 04322nam a2200397 i 4500
999 _c392251
_d392251
001 392251
003 ES-MaUEC
005 20231024174656.0
006 a|||| o|||| 00| 0
007 cr nn 008mamaa
008 130402s2013 xxua o |||| 0|eng d
020 _a9781627033701
024 7 _a10.1007/978-1-62703-370-1
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aR857 .B54
_b2013 EB
245 0 0 _aMicroelectrode Biosensors
_cedited by Stéphane Marinesco, Nicholas Dale
250 _a1st edition 2013
264 1 _aTotowa, NJ
_bHumana Press
_c2013
300 _a1 recurso en línea (XV, 387 páginas)
_b111 ilustraciones, 45 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aNeuromethods
_x1940-6045
_v80
505 0 _aMicroelectrode Designs for Oxidase-Based Biosensors -- Microelectrode Array Fabrication and Optimization for Selective Neurochemical Detection -- The Advantage of Microelectrode Technologies for Measurement in Delicate Biological Environments Such as Brain Tissue -- Hexacyanoferrates as Mediators for Microelectrode Biosensors -- Enzyme Immobilization on Microelectrode Biosensors -- Characterization of Polymer-Enzyme Composite Biosensors for Brain Monitoring In Vivo -- Monitoring Extracellular Glutamate in the Brain by Microdialysis and Microsensors -- Sub-Second Measurements of Glutamate and Other Neurotransmitter Signaling Using Enzyme-Based Ceramic Microelectrode Arrays -- Regulation of Extracellular Concentrations of D-Serine in the Central Nervous System Revealed by D-Amino Acid Oxidase Microelectrode Biosensors -- Measurement of Purine Release with Microelectrode Biosensors -- Glucose and Lactate Monitoring Across the Rat Sleep-Wake Cycle -- Forebrain Cholinergic Systems and Cognition: New Insights Based on Rapid Detection of Choline Spikes Using Enzyme-Based Biosensors -- Carbon Nanotubes-Based Microelectrode (Bio)sensors -- Label-Free Affinity Biosensors Based on Electrochemical Impedance Spectroscopy -- Aptamer-Based Electrochemical Biosensors for the Detection of Small Molecules and Plasma Proteins -- Electrochemiluminescent Biosensors: Neuroscience Applications -- Molecularly Imprinted Polymers: Promising Advanced Materials for In Vivo Sensing.
520 _aFor molecules that are not directly electroactive, it is necessary to modify a microelectrode by grafting polymeric or enzymatic membranes capable of translating a local concentration into an electrical current, which is a concept referred to as biosensing. In Microelectrode Biosensors, experts in the field cover the topic of electrochemical biosensor technology as applied to the neurosciences.  The volume opens with a section addressing the specific issue of manufacturing biosensors that can be implanted in the central nervous system for neurotransmitter detection, and it then continues with sections on recent studies where biosensors have made a difference in bringing a new level of understanding of signaling mechanisms in neuroscience as well as recent developments in biosensor technology that have not yet been applied to implantable microelectrodes but may have great potential. Written for the Neuromethods series, this work contains the kind of detailed descriptions and implementation advice necessary to achieve successful results.   Focused and cutting-edge, Microelectrode Biosensors serves to inspire the wider neuroscience and physiology community to adopt these powerful methods in their own applications in order to move the field forward with the widespread advances that will most likely flow from the adoption of biosensing as part of the standard laboratory toolkit.
988 _aSpringer_Protocols_2013
650 7 _2embne
_9158891
_aBiosensores
776 0 8 _iPrinted edition:
_z9781627033695
776 0 8 _iPrinted edition:
_z9781627033718
776 0 8 _iPrinted edition:
_z9781493959013
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-62703-370-1
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b10/2023
_dz
_eb
_zSI