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020 _a9781493972746
024 7 _a10.1007/978-1-4939-7274-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQH438.4 .S73
_b2017 EB
245 0 0 _aStatistical Human Genetics :
_bMethods and Protocols
_cedited by Robert C. Elston
250 _a2nd edition 2017
264 1 _aNew York, NY
_bSpringer International Publishing
_c2017
300 _a1 recurso en línea (XII, 689 páginas)
_b114 ilustraciones, 64 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1666
505 0 _aStatistical Genetic Terminology -- Identification of Genotype Errors -- Detecting Pedigree Relationship Errors -- Identifying Cryptic Relationships -- Estimating Allele Frequencies -- Testing Departure from Hardy-Weinberg Proportions -- Estimating Disequilibrium Coefficients -- Detecting Familial Aggregation -- Estimating Heritability from Twin Studies -- Estimating Heritability from Nuclear Family and Pedigree Data -- Correcting for Ascertainment -- Segregation Analysis using the Unified Model -- Design Considerations for Genetic Linkage and Association Studies -- Model-based Linkage Analysis of a Quantitative Trait -- Model-based Linkage Analysis of a Binary Trait -- Model-free Linkage Analysis of a Quantitative Trait -- Model-free Linkage Analysis of a Binary Trait -- Single Marker Association Analysis for Unrelated Samples -- Single Marker Family-based Association Analysis Conditional on Parental Information -- Single Marker Family-based Association Analysis not Conditional on Parental Information -- Calibrating Population Stratification in Association Analysis -- Cross-phenotype Association Analysis using Summary Statistics from GWAS -- Haplotype Inference -- Multi-SNP Haplotype Analysis Methods for Association Analysis -- The Analysis of Ethnic Mixtures -- Detecting Multiethnic Rare Variants -- Identifying Gene Interaction Networks -- Structural Equation Modeling -- Mendelian Randomization -- Preprocessing and Quality Control for Whole Genome Sequences from the Illumina HiSeq X Platform -- Statistical Approaches for Processing and Analyzing Microbiome Data.
520 _aThe aim of this volume is to make computer programs for analyzing human genetic data more easily accessible to the beginner.Statistical Human Genetics: Methods and Protocols, Second Edition provides updated and new chapters detailing genetic terms, analysis software, and how to interpret the program outputs. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, step-by-step instructions, and tips on troubleshooting and avoiding known pitfalls.  The purpose of Statistical Human Genetics: Methods and Protocols, Second Edition is to ensure successful and meaningful results in the fast-growing field of genetic epidemiology.
988 _aSpringer_Protocols_2017
650 7 _2embne
_9140562
_aGenética humana
776 0 8 _iPrinted edition:
_z9781493972739
776 0 8 _iPrinted edition:
_z9781493972753
776 0 8 _iPrinted edition:
_z9781493984381
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4939-7274-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b12/2023
_dz
_eIG
_zSI