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020 _a9781607618454
024 7 _a10.1007/978-1-60761-845-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQP551
_b2010 EB
245 0 0 _aSmall Molecule Microarrays :
_bMethods and Protocols
_cedited by Mahesh Uttamchandani, Shao Q. Yao
250 _a1st edition 2010
264 1 _aTotowa, NJ
_bHumana Press
_c2010
300 _a1 recurso en línea (XI, 215 páginas)
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v669
505 0 _aThe Expanding World of Small Molecule Microarrays -- Construction of Photo-Cross-Linked Microarrays of Small Molecules -- Small Molecule Microarray: Functional-Group Specific Immobilization of Small Molecules -- Detecting Protein-Small Molecule Interactions Using Fluorous Small-Molecule Microarrays -- A Method for Small Molecule Microarray-Based Screening for the Rapid Discovery of Affinity-Based Probes -- Nanodroplet Chemical Microarrays and Label-Free Assays -- Nanodroplet Microarrays for High-Throughput Enzyme Screening -- The Application of the Chemical Array for Biological Study -- Peptide Arrays with a Chip -- In Situ Chemical Modification of Peptide Microarrays: Characterization by Desorption/Ionization on Silicon Nanowires -- In Situ Chemical Modification of Peptide Microarrays: Application to the Study of the Antibody Responses to Methylated Antigens -- Peptide Microarrays on Coated Silicon Slides for Highly Sensitive Antibody Detection -- Antibody Signatures Defined by High-Content Peptide Microarray Analysis -- High Density Peptide Microarrays for Proteome-Wide Fingerprinting of Kinase Activities in Cell Lysates -- A Peptide Microarray for Detecting Protein Kinase Activity in Cell Lysates -- Chemical Microarrays Constructed by Selective Attachment of Hydrazide-Conjugated Substances to Epoxide Surfaces and Their Applications -- A Microarray-Based Method to Perform Nucleic Acid Selections.
520 _aSmall molecule microarrays (SMM) were introduced just a decade ago in 1999 and, within a short space of time, have already established themselves as a vibrant, next generation platform for high-throughput screening. Small Molecule Microarrays: Methods and Protocols showcases a collection of contributions guiding researchers toward ways in which small molecule microarray technology may be deployed for multiplexed screening and profiling. Organized by the categories of small molecules presented on the microarrays, this detailed volume describes in-depth techniques for chemical libraries, peptide libraries, and carbohydrate microarrays. Written in the highly successful Methods in Molecular Biology™ series, chapters contain brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, vital tips on troubleshooting this often difficult technology, and advice on avoiding known pitfalls. Authoritative and cutting-edge, Small Molecule Microarrays: Methods and Protocols provides meticulous depictions of key hands-on experience and seeks to inspire a future generation of microarray practitioners to take this significant technology forward.
988 _aSpringer_Protocols_2010
650 7 _2embne
_9141385
_aGenética molecular
650 7 _2embne
_9670812
_aMicromatrices de ADN
776 0 8 _iPrinted edition:
_z9781607618447
776 0 8 _iPrinted edition:
_z9781607618461
776 0 8 _iPrinted edition:
_z9781493958153
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-60761-845-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b11/2023
_dz
_eIG
_zSI