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020 _a9781627036108
024 7 _a10.1007/978-1-62703-610-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQK981
_b2014 EB
245 0 0 _aViral Vector Approaches in Neurobiology and Brain Diseases
_cedited by Riccardo Brambilla
250 _a1st edition 2014
264 1 _aTotowa, NJ
_bHumana Press
_c2014
300 _a1 recurso en línea (XIII, 347 páginas)
_b51 ilustraciones, 34 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aNeuromethods
_x1940-6045
_v82
505 0 _aLentiviral Vectors as Research Tools in Neurobiology: Design and Production -- Recombinant Adenovirus in Neurobiology -- Adeno-Associated Virus-Based Vectors -- Herpes Simplex Virus 1 (HSV-1)-Based Vectors -- Alphavirus-Based Vectors -- Viral Vectors to Study Synaptic Function -- Using Viral Vectors to Study the Memory Trace in Mice -- Development of Cell-Type Specific Viral Vectors to Tease Apart the Neural Circuitry that Contributes to Drug Addiction -- Using Viral-Mediated Gene Transfer to Study Depressive-Like Behavior -- Gene Therapy for Parkinson's Disease -- Lentiviral Vectors in Huntington's Disease Research and Therapy -- Application of Viral Vectors to Motor Neuron Disorders -- In Vivo Gene Silencing by Virally Delivered MicroRNA -- Viral Manipulation of Neural Stem/Precursor Cells -- Viral Vector-Based Techniques for Optogenetic Modulation In Vivo -- Viral Vectors for Optogenetics of Hypothalamic Neuropeptides -- Viral Vectors in Primate Research: Examples from Parkinson's Disease Research.
520 _aAiming toward improvement in the safety, efficiency, and specificity of viral vectors for neurobiological research and clinical applications, Viral Vector Approaches in Neurobiology and Brain Diseases covers key aspects related to the use of viral vectors in neuroscience, with a major emphasis on basic mechanisms of synaptic plasticity, learning, and memory, as well as molecular neuropharmacology and experimental animal models of brain disorders.  The volume begins by delving into features of the viral vectors currently available in neuroscience and their production methods, and it then continues onward to examples of successful applications of viral vector technology to psychiatric and memory research, current applications of viral vector technology in the context of neurological disorders, as well as various cutting-edge applications of viral vector technology to neuroscience, including optogenetics.  Written for the Neuromethods series, the chapters of this book contain the kind of detailed description and implementation advice that promotes successful, repeatable results.   Practical and up to date, Viral Vector Approaches in Neurobiology and Brain Diseases will be useful not only to neurobiologists wishing to routinely use viral vectors in the laboratory but also to experienced scientists needing detailed new protocols for a variety of experimental applications.
988 _aSpringer_Protocols_2014
650 7 _2embne
_9139640
_aGenética vegetal
650 7 _2embne
_9139455
_aPatología vegetal
776 0 8 _iPrinted edition:
_z9781627036115
776 0 8 _iPrinted edition:
_z9781627036092
776 0 8 _iPrinted edition:
_z9781493959433
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-62703-610-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b09/2023
_dz
_eIG
_zSI