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020 _a9781627034784
024 7 _a10.1007/978-1-62703-478-4
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aQH588 .S83
_b2013 EB
245 0 0 _aEmbryonic Stem Cell Immunobiology :
_bMethods and Protocols
_cedited by Nicholas Zavazava
250 _a1st edition 2013
264 1 _aTotowa, NJ
_bHumana Press
_c2013
300 _a1 recurso en línea (XIV, 206 páginas)
_b43 ilustraciones, 27 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v1029
505 0 _aImmune Privilege of Stem Cells -- Immunogenicity of In vitro Maintained and Matured Populations: Potential Barriers to Engraftment of Human Pluripotent Stem Cell Derivatives -- Hematopoietic and Natural Killer Cell Development from Human Pluripotent Stem Cells -- Evaluation of Immunogenicity of Rat ES-Cell Derived Endothelial Cells -- Interaction of ES Cell Derived Neural Progenitor Cells with Natural Killer Cells and Cytotoxic T Cells -- Strategies to Generate Induced Pluripotent Stem Cells -- The Differentiation and Lineage Commitment of Murine Embryonic Stem Cells into Insulin Producing Cells -- Mouse ES Cell-Derived Hematopoietic Progenitor Cells -- Directed Differentiation of Embryonic Stem Cells to the T-Lymphocyte Lineage -- Development of Hematopoietic Stem and Progenitor Cells from Mouse Embryonic Stem Cells, in vitro, Supported by Ectopic Human HOXB4 Expression -- Histone Modification Profiling in Normal and Transformed Human Embryonic Stem Cells Using Micro Chromatin Immunoprecipitation, Scalable to Genome-Wide Microarray Analyses -- Combined Total Proteomic and Phosphoproteomic Analysis of Human Pluripotent Stem Cells -- Transcriptional Regulatory Mechanisms that Govern Embryonic Stem Cell Fate.
520 _aBone marrow stem cells are the most transplanted cells worldwide. These cells are used as a replacement therapy for patients suffering from a diverse number of hematopoietic diseases and immunodeficiencies.  However, the use of bone marrow cells in regenerative medicine has so far remained without much success. In the new era of pluripotent stem cells, great opportunities for establishing new therapies have opened up. The discovery of human embryonic stem cells and that of induced pluripotent (iPS) stem cells has made it possible to derive any desired tissues for regenerative medicine as iPS cell derived cells are only limited by the lack of established protocols that can be applied in humans. There is no doubt that stem cells present a new and innovative platform for establishing novel cell based therapies. The challenge is to establish new protocols that allow the successful differentiation of these cells into lineage committed cells. Embryonic Stem Cell Immunobiology: Methods and Protocols covers a variety of relevant topics, such as hematopoietic stem cells derived from ES cells, the interaction of these cells with natural killer cells or with cytotoxic T cells, and specific protocols for the derivation of hematopoietic cells and neuronal cells, to name a few. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and accessible, Embryonic Stem Cell Immunobiology: Methods and Protocols serves as an ideal guide to experts and non-experts interested in different aspects of stem cells.
988 _aSpringer_Protocols_2013
650 7 _2embne
_9160528
_aCélulas madre
776 0 8 _iPrinted edition:
_z9781627034777
776 0 8 _iPrinted edition:
_z9781627034791
776 0 8 _iPrinted edition:
_z9781493962327
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-62703-478-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b06/2023
_dz
_eIG
_zSI