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008			210602s2021 xxua o |||| 0|eng d
020			_a9781071612705
024	7		_a10.1007/978-1-0716-1270-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
050		4	_aRB147.5 _b2021 EB
245	0	0	_aMitochondrial Medicine _nVolume 3, _pManipulating Mitochondria and Disease : Specific Approaches _cedited by Volkmar Weissig, Marvin Edeas
250			_a2nd edition 2021
264		1	_aNew York, NY _bSpringer International Publising _c2021
300			_a1 recurso en línea (XV, 468 páginas) _b92 ilustraciones, 60 ilustraciones a color
336			_atexto _btxt _2rdacontent
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_aarchivo de texto _bPDF
490	0		_aMethods in Molecular Biology _x1940-6029 _v2277
505	0		_aAllotopic Expression of ATP6 in the Mouse as a Transgenic Model of Mitochondrial Disease -- Mitochondrial Transplantation for Ischemia Reperfusion Injury -- Quantitatively Controlled Intercellular Mitochondrial Transfer by Cell Fusion-Based Method Using a Microfluidic Device -- Lipophilic Conjugates for Carrier-Free Delivery of RNA Importable Into Human Mitochondria -- Drug Discovery Assay to Identify Modulators of the Mitochondrial Ca2+ Uniporter -- Cytoplasmic Transfer Methods for Studying the Segregation of Mitochondrial DNA in Mice -- Electron Attachment to Isolated Molecules as a Probe To Understand Mitochondrial Reductive Processes -- Assessment of Short- and Medium-Chain Fatty Acids on Mitochondrial Function in Severe Inflammation -- Assessment of the Effects of Drugs on Mitochondrial Respiration -- The Ndufs4 Knockout Mouse: A Dual Threat Model of Childhood Mitochondrial Disease and Normative Aging -- Suborganellar Localisation of Mitochondrial Proteins and Transcripts in Human Cells -- In vivo Assessment of Mitochondrial Oxygen Consumption -- Update of Mitochondrial Network Analysis by Imaging: Proof of Technique in Schizophrenia -- Heterologous Inferential Analysis (HIA) and other Emerging Concepts In Understanding Mitochondrial Variation in Pathogenesis: There is no More Low Hanging Fruit -- Accurate Measurement of Cellular and Cell-Free Circulating Mitochondrial DNA Content from Human Blood Samples Using Real Time Quantitative PCR -- Measurement of Mitochondrial Respiration in Platelets -- Isolation and Electron Microscopic Analysis of Liver Cancer Cell Mitochondria -- Assessment of Mitochondrial Reactive Oxygen Species and Redox Regulation in Stem Cells -- Single Cell Approaches for Studying the Role of Mitochondrial DNA in Neurodegenerative Disease -- A New Method for Sequencing the Mitochondrial Genome by Using Long Read Technology -- Mitochondrial DNA as a Sensitive Biomarker of UV-induced Cellular Damage in Human Skin -- Isolation of Mitochondria-associated ER Membranes (MAMs), Synaptic MAMs and Glycosphingolipid Enriched Microdomains (GEMs) from Brain Tissues and Neuronal Cells -- Mitochondrial Diagnostics: A Discovery-Based Biochemical Platform for Phenotyping Human Peripheral Blood Cell Mitochondria -- Bioenergetic Profiling Of Human Pluripotent Stem Cells -- Integrative Methods for Studying Cardiac Energetics -- Isolation of Mitochondria from Retinal Pigment Epithelial Cell Cultures and an Application Of High Resolution Respirometric Assay (XFe96 Seahorse assay) -- The Isolation and Deep Sequencing of Mitochondrial DNA -- Ultrastructure of the Mitochondria-Associated Membranes in Human Tumor Specimens. .
520			_aThis second edition offers 88 chapters divided among three volumes providing the most comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine. Volume III guides readers through chapters on intercellular mitochondrial transfer, Cytoplasmic transfer methods, Ndufs4 knockout mouse, in vivo assessment of mitochondrial oxygen consumption, mitochondrial network analysis by imaging, mitochondrial respiration in platelets, Heterologous Inferential Analysis (HIA), bioenergetic profiling, integrative methods for studying cardiac energetics, and isolation and deep sequencing of mitochondrial DNA.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Mitochondrial Medicine, Second Edition, Volume 3: Manipulating Mitochondria and Disease- Specific Approaches aims to be a comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine.
988			_aSpringer_Protocols_2021
650		7	_2embne _9147980 _aMitocondrias
650		7	_2embne _9168790 _aMetabolismo _xTrastornos
776	0	8	_iPrinted edition: _z9781071612699
776	0	8	_iPrinted edition: _z9781071612712
776	0	8	_iPrinted edition: _z9781071612729
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-1270-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_b07/2023 _dz _eb _zSI