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020 _a9781071611388
024 7 _a10.1007/978-1-0716-1138-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRA652
_b2021 EB
245 0 0 _aClinical Epidemiology :
_bPractice and Methods
_cedited by Patrick S. Parfrey, Brendan J. Barrett
250 _a3rd edition 2021
264 1 _aNew York, NY
_bSpringer International Publising
_c2021
300 _a1 recurso en línea (XIII, 650 páginas)
_b90 ilustraciones, 37 ilustraciones a color
336 _atexto
_btxt
_2rdacontent
337 _aelectrónico
_bc
_2rdamedia
338 _arecurso electrónico
_bcr
_2rdacarrier
347 _aarchivo de texto
_bPDF
490 0 _aMethods in Molecular Biology
_x1940-6029
_v2249
505 0 _aOn Framing the Research Question and Choosing the Appropriate Research Design -- Bias in Clinical Research -- Definitions of Bias in Clinical Research -- Research Ethics for Clinical Researchers -- Ethical, Legal, and Social Issues (ELSI) in Clinical Genetics Research -- Longitudinal Studies 1: Determinants of Risk -- Longitudinal Studies 2: Modeling Data using Multivariate Analysis -- Longitudinal Studies 3: Data Modeling using Standard Regression Models and Extensions -- Longitudinal Studies 4: Matching Strategies to Evaluate Risk -- Longitudinal Studies 5: Development of Risk Prediction Models for Patients with Chronic Disease -- Randomized Controlled Trials 1: Design -- Randomized Controlled Trials 2: Analysis -- Randomized Controlled Trials 3: Measurement and Analysis of Patient-Reported Outcomes -- Randomized Controlled Trials 4: Planning, Analysis, and Interpretation of Quality of Life Studies -- Randomized Controlled Trials 5: Biomarkers and Surrogates/Outcomes -- Randomized Controlled Trials 6: Determining the Sample Size and Power for Clinical Trials and Cohort Studies -- Randomized Controlled Trials 7: On Contamination and Estimating the Actual Treatment Effect -- Evaluation of Diagnostic Tests -- Genetic Epidemiology of Complex Phenotypes -- Qualitative Research in Clinical Epidemiology -- Evidence Based Decision Making 1: Critical Appraisal -- Evidence Based Decision Making 2: Systematic Review and Meta-Analysis -- Evidence-Based Decision Making 3: Health Technology Assessment -- Evidence-Based Decision Making 4: Clinical Practice Guidelines -- Evidence-Based Decision Making 5: Knowledge Translation and the Knowledge to Action Cycle -- Evidence-Based Decision Making 6: Administrative Databases as Secondary Data Source for Epidemiologic and Health Service Research -- Methods in Evidence-Based Decision Making 7: Health Economics in Clinical Research -- Methods in Evidence-Based Decision Making 8: A Primer for Researchers -- Changing Health-Related Behaviors 1: Patient-Oriented Research and Patient Engagement in Health Research -- Changing Health-Care Behaviors 2: On Improving the Value of Health Spending -- Changing Health-Related Behaviors 3: Lessons from Implementation Science -- Changing Health-Related Behaviors 4: Realizing Impact of Health Research through Knowledge Translation -- Changing Health-Related Behaviors 5: On Interventions to Change Physician Behaviors -- Changing Health-Related Behaviors 6: Analysis, Interpretation, and Application of Big Data.
520 _aThis third edition volume expands on the previous editions with updated chapters on longitudinal studies, randomized trials, evidence-based decisions making, and a new section on changing health-related behaviors. The chapters in this book are organized into six parts: Part One focuses on framing clinical research questions and choosing a suitable design; biases that may occur in clinical research; and the ethics associated with doing conducting research on humans. Parts Two through Four discuss designs, measurements, and analysis that pertain to evaluation of risk in longitudinal studies; assessment of therapy in controlled trials; and evaluation of diagnostic tests. Part Five presents methods used in various components of evidence-based decision-making; and Part Six highlights interventions focused on changing health-related behaviors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of various types of bias, step-by-step, readily reproducible protocols for different research designs, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Clinical Epidemiology: Methods and Protocols, Third Edition is a valuable resource for clinicians and researchers who want to expand their works to humans and use their findings in the health system.
988 _aSpringer_Protocols_2021
650 7 _2embne
_9138405
_aEpidemiología
_vManuales de laboratorio
776 0 8 _iPrinted edition:
_z9781071611371
776 0 8 _iPrinted edition:
_z9781071611395
776 0 8 _iPrinted edition:
_z9781071611401
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-0716-1138-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b08/2023
_dz
_eu
_zSI